Postdoctoral Researcher Program in Dental Public Health, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
College of Dentistry, The Ohio State University, Columbus, Ohio, United States of America.
PLoS One. 2024 Aug 12;19(8):e0306367. doi: 10.1371/journal.pone.0306367. eCollection 2024.
This systematic review aims to evaluate the potential benefits and underlying mechanisms of combining SDF with light curing, based on available studies.
A systematic search of publications was conducted with the keywords "silver diamine fluoride" or "silver fluoride" and "dental light curing," "LED curing," "dental laser," and "dental polymerization" in 4 databases: PubMed, EBSCO, Scopus, and Google Scholar to identify English-language articles published up to March 2023. Duplicate publications were deleted. Two reviewers screened the titles and abstracts and excluded irrelevant publications. The full text of the remaining publications was retrieved. Studies investigating the effect of light-curing on SDF-treated carious lesions were included.
The 175 publications initially found included 5 laboratory studies investigating the effects of light curing on 38% SDF-treated dentine carious lesions, but no clinical study was found. Four of these studies were conducted on extracted primary teeth, and one was on extracted permanent teeth. SDF with light curing increased microhardness (n = 3, p < .05) showed a higher mineral density (n = 1, p < .041) and had more silver ion precipitation in infected dentine (n = 1, p < .016) compared to SDF without light curing. Moreover, no significant differences in the antibacterial activity were observed between SDF with light curing and SDF alone (n = 1, p > .05).
Drawing from the limited number of laboratory studies, incorporating light curing subsequent to the SDF application yields potential favorable outcomes that include augmented microhardness, elevated mineral density, and heightened silver ion precipitation within infected dentine. Future clinical research is required to confirm or refute the benefit of light curing on SDF-treated carious lesions.
本系统评价旨在评估基于现有研究,将 SDF 与光固化联合应用的潜在益处和潜在机制。
使用“silver diamine fluoride”或“silver fluoride”和“dental light curing”、“LED curing”、“dental laser”和“dental polymerization”等关键词,在 4 个数据库(PubMed、EBSCO、Scopus 和 Google Scholar)中进行了文献检索,以查找截至 2023 年 3 月发表的英文文章。删除重复发表的文章。两名审查员筛选标题和摘要,并排除不相关的出版物。检索并保留剩余出版物的全文。纳入研究光固化对 SDF 处理龋损影响的研究。
最初发现的 175 篇文献中包括 5 项研究 38% SDF 处理牙本质龋损的光固化效果的实验室研究,但未发现临床研究。其中 4 项研究在离体乳恒牙上进行,1 项在离体恒磨牙上进行。与未用光固化的 SDF 相比,SDF 联合光固化提高了微硬度(n = 3,p <.05),显示出更高的矿物质密度(n = 1,p <.041),并在感染牙本质中沉淀更多的银离子(n = 1,p <.016)。此外,光固化 SDF 与单独使用 SDF 的抗菌活性无显著差异(n = 1,p >.05)。
根据有限数量的实验室研究,SDF 应用后进行光固化可能会产生有益的结果,包括增加微硬度、提高矿物质密度和增加感染牙本质中的银离子沉淀。需要进行未来的临床研究来证实或反驳光固化对 SDF 处理龋损的益处。