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一项关于38%氟化银氨溶液结合光固化治疗乳牙牙本质龋的临床试验。

A Clinical Trial of 38% Silver Diamine Fluoride With Light Curing in Arresting Dentine Caries in Primary Teeth.

作者信息

Min Saw Nay, Duangthip Duangporn, Phyo Win Myat, Somboonsavatdee Anupap, Samaranayake Lakshman, Detsomboonrat Palinee

机构信息

Postdoctoral Fellowship, Department of Community Dentistry, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.

College of Dentistry, The Ohio State University, Columbus, Ohio, USA.

出版信息

Int Dent J. 2025 Jun;75(3):2084-2092. doi: 10.1016/j.identj.2024.12.030. Epub 2025 Jan 30.

DOI:10.1016/j.identj.2024.12.030
PMID:39884902
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12142778/
Abstract

OBJECTIVE

This study aimed to compare the effectiveness of semi-annual application of 38% silver diamine fluoride (SDF) with and without light curing in arresting dentine caries in primary teeth.

METHODS

Children aged 5-7 years with at least 1 active dentine carious lesion were randomly allocated into: Group 1 (38% SDF with light curing: applied SDF for 10 seconds and exposed to LED light for 20 seconds) and Group 2 (38% SDF without light curing: applied SDF for 10 seconds and isolated for 20 seconds). Both interventions were repeated every 6 months. At the baseline, demographic data, oral health-related behaviors and clinical parameters of the children were collected. The activity of carious lesion was assessed using the visual-tactile method and adverse effects, if any, were recorded at both 6-month and 12-month follow-up periods by the same examiner. Intention-to-treat analysis was employed to analyze the data.

RESULTS

At baseline, 40 children (218 lesions) and 37 children (261 lesions) were recruited into Group 1 and Group 2. There were no significant differences between the 2 groups in terms of demographic data, oral health-related behaviors, and clinical parameters of the children at baseline (P > .05). After 12 months, 66 out of 77 children (85.74%) remained in the study. There was no significant difference in caries arrest rate between Group 1 (74.8%) and Group 2 (69.0%) with P = .161.

CONCLUSION

The semi-annual application of 38% SDF with or without light curing is equally effective in arresting dentine carious lesions in primary teeth. The addition of light curing to SDF-treated teeth has no significant effect in arresting dental caries in primary teeth.

摘要

目的

本研究旨在比较每半年应用一次38%氟化银氨(SDF)并光照固化与未光照固化在阻止乳牙牙本质龋方面的效果。

方法

将年龄在5至7岁且至少有1处活动性牙本质龋损的儿童随机分为:第1组(38% SDF光照固化组:涂抹SDF 10秒,然后接受LED光照20秒)和第2组(38% SDF未光照固化组:涂抹SDF 10秒,隔离20秒)。两种干预措施均每6个月重复一次。在基线时,收集儿童的人口统计学数据、口腔健康相关行为和临床参数。采用视诊-探诊法评估龋损的活动性,并由同一名检查者在6个月和12个月的随访期记录任何不良反应。采用意向性分析来分析数据。

结果

在基线时,第1组招募了40名儿童(218处龋损),第2组招募了37名儿童(261处龋损)。两组儿童在基线时的人口统计学数据、口腔健康相关行为和临床参数方面无显著差异(P > 0.05)。12个月后,77名儿童中有66名(85.74%)仍在研究中。第1组(74.8%)和第2组(69.0%)的龋病阻止率无显著差异,P = 0.161。

结论

每半年应用一次38% SDF并光照固化或未光照固化在阻止乳牙牙本质龋损方面同样有效。在SDF治疗的牙齿上增加光照固化对阻止乳牙龋齿没有显著效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2722/12142778/e2c325d043a0/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2722/12142778/e2c325d043a0/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2722/12142778/e2c325d043a0/gr1.jpg

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本文引用的文献

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PLoS One. 2024 Aug 12;19(8):e0306367. doi: 10.1371/journal.pone.0306367. eCollection 2024.
2
Enhanced effectiveness of silver diamine fluoride application with light curing on natural dentin carious lesions: an in vitro study.氟化亚锡联合光固化治疗天然牙本质龋损的疗效增强:一项体外研究
Odontology. 2023 Apr;111(2):439-450. doi: 10.1007/s10266-022-00755-z. Epub 2022 Oct 21.
3
Silver Diamine Fluoride (SDF) Efficacy in Arresting Cavitated Caries Lesions in Primary Molars: A Systematic Review and Metanalysis.
银氨氟化溶液(SDF)在抑制乳磨牙龋损进展中的疗效:系统评价和荟萃分析。
Int J Environ Res Public Health. 2022 Oct 9;19(19):12917. doi: 10.3390/ijerph191912917.
4
Is Silver Diamine Fluoride Effective in Arresting Enamel Caries? A Randomized Clinical Trial.银氨溶液在抑制釉质龋中的效果如何?一项随机临床试验。
Int J Environ Res Public Health. 2022 Jul 24;19(15):8992. doi: 10.3390/ijerph19158992.
5
Ion Concentration of Silver Diamine Fluoride Solutions.银氨氟化溶液的离子浓度。
Int Dent J. 2022 Dec;72(6):779-784. doi: 10.1016/j.identj.2022.04.005. Epub 2022 May 13.
6
Application of Er,Cr:YSGG laser versus photopolymerization after silver diamine fluoride in primary teeth.Er,Cr:YSGG 激光与氟银氨化合物处理后的光聚合在乳恒牙的应用。
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7
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8
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9
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