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Prediction of overall survival in stage II and III colon cancer through machine learning of rapidly-acquired proteomics.

作者信息

Xu Kailun, Yin Xiaoyang, Chen Hui, Huang Yuhui, Zheng Xi, Zhou Biting, Cai Xue, Gao Huanhuan, Tian Miaomiao, Hu Sijun, Zheng Shu, Yuan Changzheng, Nie Yongzhan, Guo Tiannan, Shao Yingkuan

机构信息

Department of Breast Surgery and Oncology (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Key Laboratory of Molecular Biology in Medical Sciences, Zhejiang, China), Cancer Institute, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

Zhejiang Provincial Clinical Research Center for Cancer, Hangzhou, Zhejiang, China.

出版信息

Cell Discov. 2024 Aug 13;10(1):85. doi: 10.1038/s41421-024-00707-7.

DOI:10.1038/s41421-024-00707-7
PMID:39134531
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11319451/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/720c/11319451/cb7086d7a77a/41421_2024_707_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/720c/11319451/cb7086d7a77a/41421_2024_707_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/720c/11319451/cb7086d7a77a/41421_2024_707_Fig1_HTML.jpg

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本文引用的文献

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J Pathol Clin Res. 2022 Nov;8(6):495-508. doi: 10.1002/cjp2.294. Epub 2022 Sep 22.
2
ENO2 Promotes Colorectal Cancer Metastasis by Interacting with the LncRNA CYTOR and Activating YAP1-Induced EMT.ENO2 通过与 lncRNA CYTOR 相互作用并激活 YAP1 诱导的 EMT 促进结直肠癌转移。
Cells. 2022 Aug 1;11(15):2363. doi: 10.3390/cells11152363.
3
Mitochondrial dysfunction induces radioresistance in colorectal cancer by activating [Ca]-PDP1-PDH-histone acetylation retrograde signaling.
线粒体功能障碍通过激活 [Ca]-PDP1-PDH-组蛋白乙酰化逆行信号诱导结直肠癌细胞放射抵抗。
Cell Death Dis. 2021 Sep 6;12(9):837. doi: 10.1038/s41419-021-03984-2.
4
Specific activation of glycolytic enzyme enolase 2 in BRAF V600E-mutated colorectal cancer.BRAF V600E 突变型结直肠癌中糖酵解酶烯醇酶 2 的特异性激活。
Cancer Sci. 2021 Jul;112(7):2884-2894. doi: 10.1111/cas.14929. Epub 2021 May 14.
5
The role of PIAS3, p-STAT3 and ALR in colorectal cancer: new translational molecular features for an old disease.PIAS3、p-STAT3 和 ALR 在结直肠癌中的作用:一种古老疾病的新转化分子特征。
Eur Rev Med Pharmacol Sci. 2020 Oct;24(20):10496-10511. doi: 10.26355/eurrev_202010_23402.
6
Deep learning for prediction of colorectal cancer outcome: a discovery and validation study.深度学习预测结直肠癌结局:一项探索性和验证性研究。
Lancet. 2020 Feb 1;395(10221):350-360. doi: 10.1016/S0140-6736(19)32998-8.
7
International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study.共识免疫评分用于结肠癌分类的国际验证:预后和准确性研究。
Lancet. 2018 May 26;391(10135):2128-2139. doi: 10.1016/S0140-6736(18)30789-X. Epub 2018 May 10.
8
High-Risk Stage II Colon Cancer: Not All Risks Are Created Equal.高危 II 期结肠癌:并非所有风险都平等。
Ann Surg Oncol. 2018 Jul;25(7):1980-1985. doi: 10.1245/s10434-018-6484-8. Epub 2018 Apr 19.
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What We Know About Stage II and III Colon Cancer: It's Still Not Enough.我们对II期和III期结肠癌的了解:仍然不够。
Target Oncol. 2017 Jun;12(3):265-275. doi: 10.1007/s11523-017-0494-5.
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