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益生菌预防阴道感染:一项系统评价。

Probiotics for the Prevention of Vaginal Infections: A Systematic Review.

作者信息

Zuñiga Vinueza Andrea M

机构信息

School of Medicine, Universidad Catolica de Santiago de Guayaquil, Guayaquil, ECU.

出版信息

Cureus. 2024 Jul 13;16(7):e64473. doi: 10.7759/cureus.64473. eCollection 2024 Jul.

Abstract

Probiotics, particularly strains, have been proposed as an alternative or adjunct therapy for bacterial vaginosis (BV) and vulvovaginal candidiasis (VVC) due to their potential to restore a healthy vaginal microbiota. This systematic review evaluated 11 randomized controlled trials with a Jadad score greater than three, indicating high-quality studies based on criteria such as randomization, blinding, and dropout rates. The review demonstrated significant improvements in clinical outcomes and vaginal microbiota restoration. However, variability in results highlights the need for further research.

摘要

由于益生菌,特别是某些菌株,有恢复健康阴道微生物群的潜力,因此已被提议作为细菌性阴道病(BV)和外阴阴道念珠菌病(VVC)的替代或辅助治疗方法。本系统评价评估了11项Jadad评分大于3的随机对照试验,这表明这些研究基于随机化、盲法和失访率等标准属于高质量研究。该评价表明临床结局和阴道微生物群恢复有显著改善。然而,结果的变异性凸显了进一步研究的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3a3/11318795/e671062db272/cureus-0016-00000064473-i01.jpg

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