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嗜酸性肌间神经节炎:一名14岁男性病例。

Eosinophilic myenteric ganglionitis: A case in a 14-year-old-male.

作者信息

Price Anthony, Rastegarlari Tandis, Khowaja Sanober, Thompson Kade, Lahiji Arian P, Felicella Michelle M, He Jing, Goodwin Annie

机构信息

John Sealy School of Medicine The University of Texas Medical Branch at Galveston Galveston Texas USA.

Present address: 1005 Harborside Drive Galveston 77555 Texas USA.

出版信息

JPGN Rep. 2024 Jul 8;5(3):389-393. doi: 10.1002/jpr3.12108. eCollection 2024 Aug.

Abstract

Chronic intestinal pseudo-obstruction (CIPO) is a rare, severe, and often debilitating condition that can result in significant morbidity and mortality amongst the pediatric population. Eosinophilic myenteric ganglionitis (EMG) is a rare inflammatory neuropathy of the myenteric plexus with characteristic eosinophilic infiltration with and without hypogangliosis. The disorder has been previously documented as a cause of CIPO. We report the case of a 14-year-old male with no clear obstructive cause who, after multiple visits with a myriad of tests and workups, underwent surgical exploratory laparoscopy with the pathology returning a diagnosis of EMG with unique lymphocytic and eosinophilic cell components.

摘要

慢性肠道假性梗阻(CIPO)是一种罕见、严重且常使人衰弱的病症,可导致儿科人群出现显著的发病率和死亡率。嗜酸性肌间神经节炎(EMG)是一种罕见的肌间神经丛炎性神经病变,具有特征性的嗜酸性浸润,伴或不伴有神经节减少。该病症先前已被记录为CIPO的一个病因。我们报告了一例14岁男性病例,其无明确的梗阻原因,在多次就诊并进行了大量检查和诊断后,接受了手术探查性腹腔镜检查,病理结果显示为具有独特淋巴细胞和嗜酸性细胞成分的EMG诊断。

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