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双侧超声引导下竖脊肌平面阻滞用于重大创伤性脊柱手术术后镇痛:一项随机对照试验。

Bilateral ultrasound-guided erector spinae plane block for postoperative pain relief in major traumatic spine surgery: A randomized controlled trial.

作者信息

Pegu Baby, Gupta Babita, Ayub Arshad

机构信息

Department of Anaesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi, India.

Department of Anaesthesiology, Pain Medicine and Critical Care, JPNATC, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Saudi J Anaesth. 2024 Jul-Sep;18(3):352-359. doi: 10.4103/sja.sja_694_23. Epub 2024 Jun 4.

Abstract

INTRODUCTION

Spine fixation surgery for traumatic vertebral fractures is associated with severe pain and is often difficult to control. Traditionally systemic opioids have been the mainstay of analgesia for these procedures, which can lead to hyperalgesia, nausea, ileus, sedation, cognitive impairment, dependence, etc., limiting usage of opioids. The Erector spinae plane block (ESPB) is a novel ultrasound-guided procedure with easily identifiable sonoanatomy. We hypothesized that a multimodal approach involving ESPB to a conventional analgesic regimen with local infiltration for patients undergoing major traumatic spine surgeries might provide better perioperative analgesia and reduce the need for postoperative opioid requirements.

MATERIAL AND METHODS

A randomized control prospective trial was conducted on 34 ASA grade I -II patients aged 18 to 65 years who were scheduled to undergo elective posterior spine fixation surgery with ASIA B to E after traumatic spine fracture under general anesthesia. Patients were randomized to Group A which included patients who received general anesthesia with ESPB, and Group B, or the control group, included patients who received general anesthesia with systemic analgesics and postoperative local infiltration without ESPB. Intraoperative total fentanyl consumption, VAS score at 0, 3, 6, 12, 18, and 24 hours, time to activate patient-controlled analgesia (PCA) pump, total morphine consumption, and opioid-related side effects were monitored and compared in both groups.

RESULTS

Postoperative PCA morphine consumption was significantly lower in group A patients who received ESPB than those in the control group (17.06 ± 9.59 vs 37.82 ± 9.88 value = <0.0001). VAS scores at rest and movement at 0, 3, 6, 9, 12, 18, and 24 hours were significantly lower ( value = 0.05) in the ESPB group compared with the control group at all time points.

CONCLUSION

Bilateral ultrasound-guided Erector spinae plane block, when administered in traumatic spine patients undergoing spine fixation surgery, provides better analgesia with statistically decreased VAS scores and less postoperative opioid requirement.

摘要

引言

创伤性椎体骨折的脊柱固定手术会带来剧痛且往往难以控制。传统上,全身使用阿片类药物一直是这些手术镇痛的主要手段,但这可能会导致痛觉过敏、恶心、肠梗阻、镇静、认知障碍、成瘾等问题,限制了阿片类药物的使用。竖脊肌平面阻滞(ESPB)是一种新型的超声引导操作,其超声解剖结构易于识别。我们推测,对于接受重大创伤性脊柱手术的患者,采用ESPB联合传统局部浸润镇痛方案的多模式方法可能会提供更好的围手术期镇痛效果,并减少术后对阿片类药物的需求。

材料与方法

对34例年龄在18至65岁、ASA分级为I-II级、计划在全身麻醉下接受创伤性脊柱骨折后择期后路脊柱固定手术(ASIA B至E级)的患者进行了一项随机对照前瞻性试验。患者被随机分为A组,该组患者接受全身麻醉联合ESPB;B组为对照组,该组患者接受全身麻醉联合全身镇痛药及术后局部浸润但不进行ESPB。监测并比较两组患者术中芬太尼总用量、0、3、6、12、18和24小时的视觉模拟评分(VAS)、启动患者自控镇痛(PCA)泵的时间、吗啡总用量以及阿片类药物相关副作用。

结果

接受ESPB的A组患者术后PCA吗啡用量显著低于对照组(17.06±9.59 vs 37.82±9.88,P值 = <0.0001)。在所有时间点,ESPB组在0、3、6、9、12、18和24小时的静息和活动时VAS评分均显著低于对照组(P值 = 0.05)。

结论

对于接受脊柱固定手术的创伤性脊柱患者,双侧超声引导下的竖脊肌平面阻滞可提供更好的镇痛效果,VAS评分在统计学上显著降低,且术后阿片类药物需求减少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10d2/11323918/e1268fae7674/SJA-18-352-g001.jpg

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