Department of Sociology, University of Ibadan, Ibadan, Nigeria.
Sci Rep. 2024 Aug 17;14(1):19097. doi: 10.1038/s41598-024-52927-2.
Malaria is a leading cause of maternal and child mortality in urban Nigeria. Intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-SP) during pregnancy can prevent malaria but uptake is suboptimal. This cross-sectional study analyzed secondary data on 1159 urban Nigerian women from the 2015 Malaria Indicator Survey using descriptive statistics and logistic regression. The primary outcome was optimal IPTp-SP uptake (≥ 3 doses). 67% of women took any SP during pregnancy but only 39% took ≥ 3 IPTp-SP doses as recommended. Region and wealth index significantly predicted optimal IPTp-SP uptake while education did not. Women from lower-income regions in the urban areas were less likely to receive optimal IPTp-SP. Strategies to increase IPTp-SP uptake in urban Nigeria should target low-income regions and women of lower socioeconomic status. Logistic regression identified actionable factors for improving antenatal malaria prevention. Optimal IPTp-SP uptake remains suboptimal across urban Nigeria, threatening maternal and child health.
疟疾是尼日利亚城市地区孕产妇和儿童死亡的主要原因。孕期采用磺胺多辛-乙胺嘧啶（IPTp-SP）间歇性预防治疗可以预防疟疾，但接受率不理想。本横断面研究使用描述性统计和逻辑回归分析了来自 2015 年疟疾指标调查的 1159 名尼日利亚城市女性的二次数据。主要结局是最佳 IPTp-SP 使用率（≥3 剂）。67%的孕妇服用了任何 SP，但只有 39%的孕妇按照建议服用了≥3 剂 IPTp-SP。地区和财富指数显著预测了最佳 IPTp-SP 使用率，而教育程度则没有。城市地区低收入地区的妇女接受最佳 IPTp-SP 的可能性较小。在尼日利亚城市地区增加 IPTp-SP 使用率的策略应针对低收入地区和社会经济地位较低的妇女。逻辑回归确定了改善产前疟疾预防的可操作因素。尼日利亚城市地区的最佳 IPTp-SP 使用率仍然不理想，这对母婴健康构成威胁。
