Almass Ahmed A, Boumarah Dhuha N, Al-Ali Zhara, Salim Alaa A, Dohal Ahlam A, Al Duhileb Mohammed
King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Khobar, Saudi Arabia.
Department of General Surgery, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Khobar, Saudi Arabia.
Int J Surg Case Rep. 2024 Sep;122:110166. doi: 10.1016/j.ijscr.2024.110166. Epub 2024 Aug 13.
The occurrence of more than one tumor originating from the same or different organs is the definition of multiple primary tumors. According to the time of diagnosis, these tumors are classified into two types: metachronous and synchronous tumors. Trichoblastoma is a rare benign skin tumor that is rarely involved in multiple primary tumors, especially in patients with breast cancer.
A 60-year-old male with left breast and lateral chest wall masses. Lastly, he has been diagnosed with invasive ductal carcinoma of the left breast and chest wall trichoblastoma as metachronous primary tumors with no significant genetic background.
With the development in the medical field, such tumors are being encountered more. Some authors suggest a relationship between these tumors and genetic mutations. Although rare trichoblastomas can be transformed into malignant tumors and get metastasized.
The diagnosis and management of primary tumors can be challenging in some cases. Researchers should focus on further exploration of the genetic bases and risk factors of such tumors.
起源于同一或不同器官的一个以上肿瘤的发生即为多原发性肿瘤的定义。根据诊断时间,这些肿瘤分为两种类型:异时性和同时性肿瘤。毛母细胞瘤是一种罕见的良性皮肤肿瘤,很少累及多原发性肿瘤,尤其是乳腺癌患者。
一名60岁男性,左乳房和侧胸壁有肿块。最终,他被诊断为左乳浸润性导管癌和胸壁毛母细胞瘤,为异时性原发性肿瘤,无显著遗传背景。
随着医学领域的发展,此类肿瘤越来越常见。一些作者认为这些肿瘤与基因突变之间存在关联。尽管罕见的毛母细胞瘤可转变为恶性肿瘤并发生转移。
在某些情况下,原发性肿瘤的诊断和管理可能具有挑战性。研究人员应专注于进一步探索此类肿瘤的遗传基础和危险因素。