Kos Eva, Cigić Valentina, Bušić Mladen, Bjeloš Mirjana, Miletić Daliborka, Kuzmanović Elabjer Biljana
University Eye Clinic, University Hospital "Sveti Duh", Sveti Duh 64, Zagreb 10000, Croatia.
Faculty of Dental Medicine and Health Care Osijek, Faculty of Medicine Osijek, University Josip Juraj Strossmayer in Osijek, Osijek 31000, Croatia.
Int J Ophthalmol. 2024 Aug 18;17(8):1418-1422. doi: 10.18240/ijo.2024.08.05. eCollection 2024.
To invastigate intra- and interobserver reliability of interferometry, tear meniscus height (TMH) measurement and meibography (MBG) of an ocular surface analyzer, LacryDiag (Quantel Medical, France).
Five consecutive measurements and subsequent analysis of interferometry, TMH, and MBG were recorded by two examiners using the LacryDiag. To assess intra- and interobserver reliability, we used Cohen's kappa for categorical variables (interferometry), or intraclass correlation coefficient for continuous variables (TMH, MBG).
Thirty eyes of 30 examinees were included. For both observers, there was excellent intraobserver reliability for MBG (0.955 and 0.970 for observer 1 and 2, respectively). Intraobserver reliability for observer 1 was substantial for interferometry (0.799), and excellent for TMH (0.863). Reliability for observer 2 was moderate for interferometry (0.535) and fair to good for TMH (0.431). Interobserver reliability was poor for interferometry (0.074) and fair to good for TMH (0.680) and MBG (0.414).
LacryDiag ocular surface analyzer in our study proves to be a reliable noninvasive tool for the evaluation of TMH and MBG. As for interferometry, poor interobserver reliability, fair to good intraobserver reliability for observer 1, and moderate for observer 2, leave room for improvement.
研究法国Quantel Medical公司生产的眼表分析仪LacryDiag的干涉测量、泪膜半月板高度（TMH）测量及睑板腺照相（MBG）在观察者内和观察者间的可靠性。
两名检查者使用LacryDiag对干涉测量、TMH和MBG进行连续五次测量并随后进行分析。为评估观察者内和观察者间的可靠性，对于分类变量（干涉测量）我们使用Cohen's kappa系数，对于连续变量（TMH、MBG）我们使用组内相关系数。
纳入30名受试者的30只眼。对于两名观察者，MBG的观察者内可靠性均极佳（观察者1和2分别为0.955和0.970）。观察者1的干涉测量观察者内可靠性为实质性（0.799），TMH为极佳（0.863）。观察者2的干涉测量可靠性为中等（0.535），TMH为一般至良好（0.431）。观察者间干涉测量可靠性较差（0.074），TMH为一般至良好（0.680），MBG为中等（0.414）。
在我们的研究中，LacryDiag眼表分析仪被证明是评估TMH和MBG的可靠无创工具。至于干涉测量，观察者间可靠性较差，观察者1的观察者内可靠性一般至良好，观察者2的为中等，仍有改进空间。
