Department of Neurosurgery, University of California, San Francisco, San Francisco, California, USA.
Division of Neuro-Oncology, University of California San Francisco and Weill Institute for Neurosciences, San Francisco, California, USA.
Neuro Oncol. 2024 Nov 4;26(11):1951-1963. doi: 10.1093/neuonc/noae127.
The disease course and clinical outcome for brain tumor patients depend not only on the molecular and histological features of the tumor but also on the patient's demographics and social determinants of health. While current investigations in neuro-oncology have broadly utilized artificial intelligence (AI) to enrich tumor diagnosis and more accurately predict treatment response, postoperative complications, and survival, equity-driven applications of AI have been limited. However, AI applications to advance health equity in the broader medical field have the potential to serve as practical blueprints to address known disparities in neuro-oncologic care. In this consensus review, we will describe current applications of AI in neuro-oncology, postulate viable AI solutions for the most pressing inequities in neuro-oncology based on broader literature, propose a framework for the effective integration of equity into AI-based neuro-oncology research, and close with the limitations of AI.
脑肿瘤患者的疾病进程和临床结局不仅取决于肿瘤的分子和组织学特征,还取决于患者的人口统计学特征和健康的社会决定因素。虽然神经肿瘤学领域的当前研究广泛利用人工智能 (AI) 来丰富肿瘤诊断,并更准确地预测治疗反应、术后并发症和生存情况,但 AI 的公平性应用受到了限制。然而,将 AI 应用于提高更广泛医疗领域的公平性,有可能成为解决神经肿瘤学护理中已知差异的实际蓝图。在本次共识综述中,我们将描述 AI 在神经肿瘤学中的当前应用,根据更广泛的文献,推测 AI 在神经肿瘤学中最紧迫的不公平问题的可行解决方案,提出将公平性有效纳入基于 AI 的神经肿瘤学研究的框架,并以 AI 的局限性作为结尾。