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基于植物的银纳米粒子的合成、表征方法、应用和毒性:全面综述。

Plant-based synthesis, characterization approaches, applications and toxicity of silver nanoparticles: A comprehensive review.

机构信息

Department of Applied Science and Humanities, Vimal Jyothi Engineering College, Kannur 670632, India.

Department of Chemistry, St. Aloysius College (Autonomous), Mangalore 575003, India.

出版信息

J Biotechnol. 2024 Nov 10;394:135-149. doi: 10.1016/j.jbiotec.2024.08.009. Epub 2024 Aug 17.

Abstract

The development of an environmentally benign method for the synthesis of nanoparticles has been facilitated by green chemistry. "Green synthesis" uses a range of biological elements like microbes, plants, and other biodegradable materials to produce NPs. Active biomolecules that are secreted by natural strains and present in the plant extracts serve as both reducing and capping/stabilizing agents. Microorganisms' intracellular enzymes can reduce metal ions, which explains how NPs might potentially nucleate. Plant-based synthesis of nanomaterials is particularly promising owing to abundant resources, simplicity of synthesis, and low cost. Silver nanoparticles (AgNPs) are attracting great attention in the research community due to their wide variety of applications in chemistry, food technology, microbiology, and biomedicine. Recent years have seen a large amount of research on the bio-genic synthesis of AgNPs employing biomaterials like plant extract and bacteria as reducing agents. Herein we discuss a thorough overview of the plant-based synthesis of silver nanoparticles (AgNPs), characterization approaches, applications, and toxicity. The review covers the green chemistry and nanotechnology elements of producing AgNPs, including a thorough discussion of the plant extract mediated synthesis, detailed formation mechanism, and a well-balanced emphasis on hazards and advantages. Based on current developments, the optimisation strategies, applications, and interdisciplinary characteristics are also covered in detail.

摘要

绿色化学促进了环境友好型纳米粒子合成方法的发展。“绿色合成”使用微生物、植物和其他可生物降解材料等一系列生物元素来生产 NPs。天然菌株分泌的活性生物分子和植物提取物中存在的活性生物分子既可以作为还原剂,也可以作为帽/稳定剂。微生物细胞内的酶可以还原金属离子,这解释了 NPs 如何可能成核。由于资源丰富、合成简单、成本低,植物基纳米材料的合成具有很大的前景。银纳米粒子 (AgNPs) 由于在化学、食品技术、微生物学和生物医学等领域的广泛应用而受到研究界的广泛关注。近年来,人们大量研究了利用植物提取物和细菌等生物材料作为还原剂的生物合成 AgNPs。本文全面综述了银纳米粒子 (AgNPs) 的植物合成、表征方法、应用和毒性。综述涵盖了生产 AgNPs 的绿色化学和纳米技术要素,包括对植物提取物介导合成的深入讨论、详细的形成机制,以及对危害和优势的均衡强调。根据目前的发展情况,还详细介绍了优化策略、应用和跨学科特性。

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