食用树莓对成年人人体测量指标和肝功能检查的影响：一项经GRADE评估的系统评价和荟萃分析。

The effects of raspberry consumption on anthropometric indices and liver function tests in adults: a GRADE-assessed systematic review and meta-analysis.

作者信息

Shahraki Jazinaki Mostafa, Barghchi Hanieh, Rahbarinejad Pegah, Pahlavani Naseh

机构信息

Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.

Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

Front Nutr. 2024 Aug 5;11:1419417. doi: 10.3389/fnut.2024.1419417. eCollection 2024.

BACKGROUND

In recent years, the therapeutic effects of raspberry have been the subject of several randomized control trials (RCTs). However, there is no consensus about the effect of raspberry consumption on anthropometric indices and liver function tests. So, the present review aims to investigate this effectiveness by conducting a meta-analysis.

METHODS

PubMed, Web of Science, and Scopus databases were searched to identify eligible randomized control trials (RCTs) up to March 2024. The overall effect sizes were estimated using the random-effects model as weighted mean difference (WMD) and 95% confidence intervals (CIs).

RESULTS

Nine studies (10 arms) with 355 participants were eligible for inclusion in this review. This meta-analysis showed that raspberry consumption did not lead to significant changes in anthropometric indices (weight, body mass index, and waist circumference) and liver function tests (aspartate aminotransferase and alanine aminotransferase).

CONCLUSION

This review revealed that raspberry consumption had no significant impact on anthropometric indices or liver function tests. However, more RCTs with a larger sample size and higher sensitivity are needed to draw definite conclusions.: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=477568, PROSPERO ID: CRD42023477568.

背景

近年来，树莓的治疗效果已成为多项随机对照试验（RCT）的研究主题。然而，对于食用树莓对人体测量指标和肝功能测试的影响尚无共识。因此，本综述旨在通过进行荟萃分析来研究这种有效性。

方法

检索了PubMed、Web of Science和Scopus数据库，以识别截至2024年3月符合条件的随机对照试验（RCT）。使用随机效应模型估计总体效应大小，以加权平均差（WMD）和95%置信区间（CIs）表示。

结果

9项研究（10个组）共355名参与者符合纳入本综述的条件。该荟萃分析表明，食用树莓不会导致人体测量指标（体重、体重指数和腰围）和肝功能测试（天冬氨酸转氨酶和丙氨酸转氨酶）发生显著变化。

结论

本综述表明，食用树莓对人体测量指标或肝功能测试没有显著影响。然而，需要更多样本量更大、灵敏度更高的随机对照试验才能得出明确结论。：https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=477568，PROSPERO编号：CRD42023477568 。