Kim Bogun, Heo Ji Yu, Xu Xiaoyue, Lee Hyunju, Pathiraja Duleepa, Kim Jae-Young, Choi Yi Hyun, Choi In-Geol, Kim Sae Hun
Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Korea.
Department of Food Bioscience and Technology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Korea.
J Anim Sci Technol. 2024 Jul;66(4):859-862. doi: 10.5187/jast.2023.e122. Epub 2024 Jul 31.
It has been reported that the administration of alleviates diseases such as osteoporosis and colitis. In this study, we report the complete genome sequence of KUFM407, a probiotic strain of LAB isolated from Korean traditional fermented food, Kimchi. Whole genome sequencing of KUFM407 was performed on the Illumina MiSeq and Oxford Nanopore MinION platform. The genome consisted of one circular chromosome (2,077,616 base pair [bp]) with a guanine cytosine (GC) content of 51.5% and one circular plasmid sequence (13,931 bp). Genome annotation identified 1,932 protein-coding genes, 15 rRNAs, and 58 tRNAs in the assembly. The function annotation of the predicted proteins revealed genes involved in the biosynthesis of bacteriocin and fatty acids. The complete genome of KUFM407 could provide valuable information for the development of new probiotic food and health supplements.
据报道，施用[具体物质未提及]可缓解骨质疏松症和结肠炎等疾病。在本研究中，我们报告了从韩国传统发酵食品泡菜中分离出的乳酸菌益生菌菌株KUFM407的完整基因组序列。KUFM407的全基因组测序在Illumina MiSeq和牛津纳米孔MinION平台上进行。该基因组由一条环状染色体（2,077,616碱基对[bp]）组成，鸟嘌呤胞嘧啶（GC）含量为51.5%，以及一条环状质粒序列（13,931 bp）。基因组注释在组装中鉴定出1,932个蛋白质编码基因、15个rRNA和58个tRNA。预测蛋白质的功能注释揭示了参与细菌素和脂肪酸生物合成的基因。KUFM407的完整基因组可为新型益生菌食品和健康补充剂的开发提供有价值的信息。
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