Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, USA.
Aspect Research Centre for Autism Practice, Autism Spectrum Australia, New South Wales, Australia.
Autism Res. 2024 Sep;17(9):1810-1817. doi: 10.1002/aur.3207. Epub 2024 Aug 21.
There is a paucity of research that explores associations between emotion dysregulation and the expression and severity of core and co-occurring characteristics of autism spectrum disorder (ASD), especially in autistic youth with co-occurring intellectual disability (ID). This study explored the interplay between developmental characteristics and emotion dysregulation, anxiety, and specific subtypes of RRBs that are elevated in autistic youth with co-occurring ID. Generalized additive models demonstrated that age, sex, language level, dysregulation, and anxiety showed unique patterns of association with subtypes of RRBs in a sample of 150 autistic youth with co-occurring ID who are non-speaking or minimally verbal. More specifically, higher anxiety levels were significantly associated with elevations in repetitive sensory motor behaviors (RSMB), self-injurious behaviors (SIB), insistence on sameness (IS), and unusual interests (UI). While emotion dysregulation was a significant predictor of UI, it demonstrated positive, albeit not significant, associations with the intensity of SIB and RSMB. Language level was a significant predictor of RSMB, such that the intensity of RSMB was higher for individuals who were non-speaking relative to those who spoke in single words. These findings provide preliminary insights into patterns of associations between emotion dysregulation, anxiety, and specific subdomains of RRBs in autistic youth with ID.
目前,关于情绪失调与自闭症谱系障碍(ASD)核心特征和共病特征的表达和严重程度之间的关联的研究很少,特别是在伴有智力障碍(ID)的自闭症青少年中。本研究探讨了在伴有共病 ID 的自闭症青少年中,发育特征与情绪失调、焦虑以及RRB 的特定亚型之间的相互作用。广义加性模型表明,在 150 名伴有 ID 的非口语或极少量言语的自闭症青少年样本中,年龄、性别、语言水平、失调和焦虑与 RRBs 的亚型有独特的关联模式。更具体地说,较高的焦虑水平与重复感觉运动行为(RSMB)、自伤行为(SIB)、坚持相同(IS)和异常兴趣(UI)的升高显著相关。虽然情绪失调是 UI 的一个重要预测因素,但它与 SIB 和 RSMB 的强度呈正相关,尽管不显著。语言水平是 RSMB 的一个重要预测因素,即相对于只说单词的人,非口语的人 RSMB 的强度更高。这些发现初步揭示了 ID 自闭症青少年中情绪失调、焦虑和 RRBs 特定子领域之间的关联模式。