Grossi Enzo, Caminada Elisa, Goffredo Michela, Vescovo Beatrice, Castrignano Tristana, Piscitelli Daniele, Valagussa Giulio, Franceschini Marco, Vanzulli Franco
Autism Research Unit, "Villa Santa Maria" Foundation, 22038 Tavernerio, Italy.
Neurorehabilitation Research Laboratory, Department of Neurological and Rehabilitation Sciences, IRCSS San Raffaele Pisana, 00163 Rome, Italy.
Brain Sci. 2021 May 21;11(6):678. doi: 10.3390/brainsci11060678.
Several instruments have been proposed to investigate restricted, repetitive behaviors (RRBs) in individuals with Autism Spectrum Disorder (ASD). Systematic video observations may overcome questionnaire and interview limitations to investigate RRBs. This study aimed to analyze stereotypic patterns through video recordings and to determine the correlation between the number and appearance of RRBs to ASD severity.
Twenty health professionals wearing a body cam recorded 780 specific RRBs during everyday activities of 67 individuals with ASD (mean age: 14.2 ± 3.72 years) for three months. Each stereotypy was classified according to its complexity pattern (i.e., simple or complex) based on body parts and sensory channels involved.
The RRBs spectrum for each subject ranged from one to 33 different patterns (mean: 11.6 ± 6.82). Individuals with a lower number of stereotypies shown a lower ASD severity compared to subjects with a higher number of stereotypies ( = 0.044). No significant differences were observed between individuals exhibiting simple ( = 40) and complex patterns ( = 27) of stereotypies on ASD severity, age, sex, and the number of stereotypes.
This study represents the first attempt to systematically document expression patterns of RRBs with a data-driven approach. This may provide a better understanding of the pathophysiology and management of RRBs.
已经提出了几种工具来调查自闭症谱系障碍（ASD）个体的受限、重复行为（RRB）。系统的视频观察可能会克服问卷调查和访谈的局限性来研究RRB。本研究旨在通过视频记录分析刻板行为模式，并确定RRB的数量和表现与ASD严重程度之间的相关性。
20名佩戴随身摄像头的健康专业人员在67名ASD个体（平均年龄：14.2±3.72岁）的日常活动中记录了780种特定的RRB，为期三个月。根据所涉及的身体部位和感觉通道，将每种刻板行为按照其复杂程度模式（即简单或复杂）进行分类。
每个受试者的RRB谱范围为1至33种不同模式（平均：11.6±6.82）。与刻板行为数量较多的受试者相比，刻板行为数量较少的个体ASD严重程度较低（P = 0.044）。在ASD严重程度、年龄、性别和刻板行为数量方面，表现出简单刻板行为模式（n = 40）和复杂刻板行为模式（n = 27）的个体之间未观察到显著差异。
本研究首次尝试采用数据驱动的方法系统记录RRB的表达模式。这可能有助于更好地理解RRB的病理生理学和管理。
