Department of Chemistry, Institute of Physical Chemistry, University of Hamburg, Hamburg, Germany.
The Hamburg Centre for Ultrafast Imaging, Hamburg, Germany.
Protein Sci. 2024 Sep;33(9):e5153. doi: 10.1002/pro.5153.
Assembly of nanoparticles into superlattices yields nanomaterials with novel properties. We have recently shown that engineered protein cages are excellent building blocks for the assembly of inorganic nanoparticles into highly structured hybrid materials, with unprecedented precision. In this study, we show that the protein matrix, composed of surface-charged protein cages, can be readily tuned to achieve a number of different crystalline assemblies. Simply by altering the assembly conditions, different types of crystalline structures were produced, without the need to further modify the cages. Future work can utilize these new protein scaffolds to create nanoparticle superlattices with various assembly geometries and thus tune the functionality of these hybrid materials.
将纳米粒子组装成超晶格可以得到具有新颖性质的纳米材料。我们最近表明，经过设计的蛋白质笼是将无机纳米粒子组装成具有前所未有的精度的高度结构化杂化材料的绝佳构建块。在这项研究中，我们表明，由带电蛋白质笼组成的蛋白质基质可以很容易地进行调整，以实现多种不同的晶体组装。只需改变组装条件，就可以在无需进一步修饰笼的情况下生成不同类型的晶体结构。未来的工作可以利用这些新的蛋白质支架来创建具有各种组装几何形状的纳米粒子超晶格，从而调整这些杂化材料的功能。
