Electroorganic and Materials Electrochemistry (EME) Division, CSIR-Central Electrochemical Research Institute, Tamil Nadu, Karaikudi, 630 003, India.
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201 002, India.
Mikrochim Acta. 2024 Aug 21;191(9):552. doi: 10.1007/s00604-024-06625-5.
N-doped hollow carbon spheres (NHCSs) with different shell thicknesses are constructed using various amounts of SiO precursor. An interconnected framework with diminished wall thickness ensures an efficient and continuous electron transport which helps to enhance the performance of NHCS. Improvement of the electrocatalytic performance was shown in the determination of antibiotic drug chloramphenicol (CAP) due to the unique hollow thin shell morphology, ample defect sites, accessible surface area, higher surface-to-volume ratio and an synergistic effect. Boosted electrocatalytic activity of 1.5 N-doped HCS (1.5 NHCS) was applied to detect CAP with a linear range and detection limit of 1-1150 µM and 0.098 µM (n = 3), respectively, with superior storage stability and considerable sensitivity. These results suggest that the proposed work can be successfully applied to the determination of CAP in milk and water samples.
采用不同量的 SiO 前体制备了具有不同壳厚的 N 掺杂中空碳球（NHCS）。具有减小的壁厚的互联框架确保了高效且连续的电子传输，这有助于提高 NHCS 的性能。由于独特的中空薄壁形态、丰富的缺陷位、可及的表面积、更高的比表面积和协同效应，在测定抗生素药物氯霉素（CAP）时表现出了改进的电催化性能。增强的 1.5N 掺杂 HCS（1.5NHCS）的电催化活性可用于检测 CAP，其线性范围和检测限分别为 1-1150µM 和 0.098µM（n=3），具有出色的存储稳定性和相当高的灵敏度。这些结果表明，所提出的工作可以成功应用于牛奶和水样中 CAP 的测定。
