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用于增强微/纳米机器人在生物医学环境中导航的势场机制与分布式学习。

Potential field mechanisms and distributed learning for enhancing the navigation of micro/nanorobot in biomedical environments.

作者信息

Zhang Junqiao, Qu Qiang, Chen Xuebo

机构信息

School of Electronics and Information Engineering, University of Science and Technology Liaoning, Anshan, 114051, China.

出版信息

Heliyon. 2024 Jul 26;10(15):e35328. doi: 10.1016/j.heliyon.2024.e35328. eCollection 2024 Aug 15.

Abstract

In complex systems, single micro/nanorobots encounter challenges related to limited loading capacity and navigation, hindering their effective utilization in targeted therapy and drug delivery. To solve these challenges, this paper explores potential field mechanisms as a means to simulate natural collective behavior. This approach aims to enhance the navigation and efficiency of micro/nanorobots in high-demand therapeutic areas. The mechanism enables micro/nanorobots to dynamically adapt to environmental gradients, minimizing off-target effects while maximizing therapeutic efficacy and enhancing robustness through redundancy. Additionally, this study introduces innovative distributed learning and cooperative control strategies. Each micro/nanorobot updates its navigation strategy through local interactions and influences with the dynamic environment. This allows micro/nanorobots to share information and improve their navigation toward therapeutic targets. The simulation results demonstrate that collective behavior and potential field mechanisms can enhance the precision and efficiency of targeted therapy and drug delivery in dynamically changing environments. In conclusion, the proposed approach can improve the limitations of single micro/nanobot, offering new possibilities for the development of advanced therapeutics and drug delivery systems.

摘要

在复杂系统中,单个微纳机器人面临着与有限负载能力和导航相关的挑战,这阻碍了它们在靶向治疗和药物递送中的有效应用。为了解决这些挑战,本文探索了潜在场机制,作为模拟自然集体行为的一种手段。这种方法旨在提高微纳机器人在高需求治疗领域的导航能力和效率。该机制使微纳机器人能够动态适应环境梯度,在最大限度提高治疗效果的同时将脱靶效应降至最低,并通过冗余增强鲁棒性。此外,本研究还引入了创新的分布式学习和协同控制策略。每个微纳机器人通过与动态环境的局部交互和影响来更新其导航策略。这使得微纳机器人能够共享信息并改善其向治疗靶点的导航。模拟结果表明,集体行为和潜在场机制可以提高在动态变化环境中靶向治疗和药物递送的精度和效率。总之,所提出的方法可以改善单个微纳机器人的局限性,为先进治疗和药物递送系统的发展提供新的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/077e/11336596/12caa9e57d59/gr1.jpg

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