Ma Yitao, Young William
Neurology, Walter Reed National Military Medical Center, Bethesda, USA.
Cureus. 2024 Jul 21;16(7):e65061. doi: 10.7759/cureus.65061. eCollection 2024 Jul.
Vagus nerve stimulation (VNS) has been used as an adjunctive therapeutic option for drug-resistant epilepsy for decades. Traditionally, the left vagus nerve is used for stimulation, while the right vagus nerve is rarely used. The long-term efficacy and safety of the right VNS (R-VNS) in humans are unknown. We presented three patients who were treated with R-VNS over a follow-up period of up to eight years. All three patients tolerated R-VNS well with minimal complications. R-VNS displayed reasonable effectiveness in all three patients. One patient had an excellent response and became seizure-free. The other two patients demonstrated a less favorable response to R-VNS compared to their previous left VNS therapy.
几十年来，迷走神经刺激术（VNS）一直被用作耐药性癫痫的辅助治疗选择。传统上，使用左侧迷走神经进行刺激，而右侧迷走神经很少使用。右侧迷走神经刺激术（R-VNS）在人类中的长期疗效和安全性尚不清楚。我们报告了三名接受R-VNS治疗长达八年的患者。所有三名患者对R-VNS耐受性良好，并发症极少。R-VNS在所有三名患者中均显示出合理的疗效。一名患者反应极佳，癫痫发作消失。与之前的左侧迷走神经刺激术治疗相比，另外两名患者对R-VNS的反应较差。
