线粒体内共生的基因组影响的体细胞观点。
A somatic view of the genomic impact of mitochondrial endosymbiosis.
机构信息
Department of Pediatrics, Section of Genetics and Metabolism, University of Colorado School of Medicine, Aurora, Colorado, United States of America.
出版信息
PLoS Biol. 2024 Aug 23;22(8):e3002756. doi: 10.1371/journal.pbio.3002756. eCollection 2024 Aug.
Abstract
The endosymbiosis of mitochondrial ancestors resulted in the transfer of genetic material on an evolutionary scale for eukaryotic species. A new study in PLOS Biology expands this to the genome of somatic cells within individuals and highlights its correlation with aging and disease.
摘要
线粒体祖先的内共生导致了遗传物质在进化尺度上向真核生物的转移。PLOS Biology 的一项新研究将其扩展到个体体细胞的基因组，并强调了其与衰老和疾病的相关性。
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