Department of Surgical Sciences, Section of Otorhinolaryngology and Head and Neck Surgery, Uppsala University, Uppsala, Sweden.
Department of Food, Nutrition and Culinary Science, Umeå University, Umeå, Sweden.
West J Nurs Res. 2024 Oct;46(10):790-798. doi: 10.1177/01939459241274342. Epub 2024 Aug 24.
The Head and Neck Patient Symptom Checklist (HNSC) is a validated 2-part instrument used to ask patients with head and neck cancer about the nutrition impact symptoms they experience (part 1) and how these interfere with their eating (part 2).
The purpose of this work was to translate and culturally adapt the HNSC into Swedish in accordance with the guidelines of the International Society for Health Economics and Outcomes Research (ISPOR).
The ISPOR guidelines include 10 steps, and these were thoroughly followed. In step 7, 9 health care professionals from the field of head and neck cancer assessed the perceived relevance (content validity) of each item in the HNSC, as well as the full HNSC. A total of 522 participants with head and neck cancer were included and followed up on 7 occasions using the HNSC to assess internal consistency.
The HNSC was translated from English into Swedish, ensuring accuracy through forward and backward translation and harmonization in the research team. Content validity for each part of the HNSC was rated excellent (scale content validity index 0.96). Internal consistency demonstrated a good Cronbach's alpha score (>0.8) across the 7 follow-up time points (from baseline [before the start of treatment] and up to 24 months posttreatment).
The HNSC has been successfully translated and culturally adapted into Swedish. The HNSC can be used in both clinical practice and research to screen for nutrition impact symptoms and symptoms that interfere with eating in patients with head and neck cancer.
ClinicalTrials.gov NCT03343236 (date of registration: November 17, 2017).
头颈部患者症状清单（HNSC）是一种经过验证的两部分工具，用于询问头颈部癌症患者他们所经历的营养影响症状（第 1 部分）以及这些症状如何影响他们的进食（第 2 部分）。
这项工作的目的是根据国际卫生经济和结果研究学会（ISPOR）的指南将 HNSC 翻译成瑞典语并进行文化适应性调整。
ISPOR 指南包括 10 个步骤，我们严格遵循了这些步骤。在步骤 7 中，来自头颈部癌症领域的 9 名医疗保健专业人员评估了 HNSC 中每个项目（包括完整的 HNSC）的感知相关性（内容有效性）。共有 522 名头颈部癌症患者参与了研究，并使用 HNSC 进行了 7 次随访，以评估内部一致性。
HNSC 从英语翻译成瑞典语，通过正向和反向翻译以及研究团队的协调确保了准确性。HNSC 的每个部分的内容有效性均被评为优秀（量表内容有效性指数 0.96）。在 7 个随访时间点（从治疗前的基线到治疗后 24 个月），内部一致性显示出良好的 Cronbach's alpha 评分（>0.8）。
HNSC 已成功翻译成瑞典语并进行了文化适应性调整。HNSC 可用于临床实践和研究，以筛查头颈部癌症患者的营养影响症状和进食障碍症状。
ClinicalTrials.gov NCT03343236（注册日期：2017 年 11 月 17 日）。
