中年及老年期新诊断的囊性纤维化
Newly diagnosed cystic fibrosis in middle and later life.
作者信息
Hunt B, Geddes D M
出版信息
Thorax. 1985 Jan;40(1):23-6. doi: 10.1136/thx.40.1.23.
Abstract
Four patients with cystic fibrosis diagnosed in middle and later life are presented. All had chronic bronchopulmonary infection with a high sweat sodium concentration, and chest radiographic evidence of upper zone bronchiectasis. Two patients had pancreatic dysfunction. Sputum culture grew mucoid Pseudomonas aeruginosa in three patients and Haemophilus influenzae in one. Ages at diagnosis were 63, 42, 40, and 35 years. These patients confirm the possibility of occasional longevity in cystic fibrosis and emphasise the need to consider the diagnosis at all ages. They also provide encouragement for younger patients.
摘要
本文介绍了4例在中年及老年期被诊断为囊性纤维化的患者。所有患者均有慢性支气管肺部感染，汗液钠浓度升高，胸部X线显示上叶支气管扩张。2例患者有胰腺功能障碍。3例患者的痰培养生长出黏液型铜绿假单胞菌，1例生长出流感嗜血杆菌。诊断时的年龄分别为63岁、42岁、40岁和35岁。这些患者证实了囊性纤维化患者偶尔可长寿的可能性，并强调了在各个年龄段都需考虑该诊断的必要性。它们也为年轻患者带来了鼓舞。
相似文献
1
Newly diagnosed cystic fibrosis in middle and later life.中年及老年期新诊断的囊性纤维化
Thorax. 1985 Jan;40(1):23-6. doi: 10.1136/thx.40.1.23.
2
[Microbiological diagnostics in the patients with cystic fibrosis].
Pneumonol Alergol Pol. 2014;82(4):327-9. doi: 10.5603/PiAP.2014.0040.
3
Haemophilus infections in cystic fibrosis.
Lancet. 1980 Aug 2;2(8188):262. doi: 10.1016/s0140-6736(80)90150-6.
4
Induced sputum compared to bronchoalveolar lavage in young, non-expectorating cystic fibrosis children.诱导痰与支气管肺泡灌洗在年轻不排痰囊性纤维化患儿中的比较。
J Cyst Fibros. 2014 Jan;13(1):106-10. doi: 10.1016/j.jcf.2013.05.013. Epub 2013 Jun 24.
5
Prevalence of cystic fibrosis pathogens in the oropharynx of healthy children and implications for cystic fibrosis care.健康儿童口咽部囊性纤维化病原体的流行情况及其对囊性纤维化治疗的影响。
J Cyst Fibros. 2012 Sep;11(5):456-7. doi: 10.1016/j.jcf.2012.04.004. Epub 2012 Apr 30.
6
Pseudomonas aeruginosa mucoid strain. Its significance in adult chest diseases.铜绿假单胞菌黏液型菌株。其在成人胸部疾病中的意义。
Am Rev Respir Dis. 1982 Nov;126(5):833-6. doi: 10.1164/arrd.1982.126.5.833.
7
A novel microbiota stratification system predicts future exacerbations in bronchiectasis.一种新的微生物组分层系统可预测支气管扩张症的未来恶化。
Ann Am Thorac Soc. 2014 May;11(4):496-503. doi: 10.1513/AnnalsATS.201310-335OC.
8
Selective media for the quantitation of bacteria in cystic fibrosis sputum.用于定量分析囊性纤维化痰液中细菌的选择性培养基。
J Med Microbiol. 1984 Apr;17(2):113-9. doi: 10.1099/00222615-17-2-113.
9
Cystic fibrosis in adults.
Lung. 2007 Mar-Apr;185(2):81-7. doi: 10.1007/s00408-006-2597-0. Epub 2007 Feb 9.
10
Bacterial infection in cystic fibrosis.囊性纤维化中的细菌感染
Arch Dis Child. 1972 Dec;47(256):908-13. doi: 10.1136/adc.47.256.908.
引用本文的文献
1
Omega-3 fatty acid supplementation for cystic fibrosis.补充ω-3脂肪酸治疗囊性纤维化
Cochrane Database Syst Rev. 2020 Apr 10;4(4):CD002201. doi: 10.1002/14651858.CD002201.pub6.
2
Antagonistic Pleiotropy in Human Disease.人类疾病中的拮抗多效性
J Mol Evol. 2020 Jan;88(1):12-25. doi: 10.1007/s00239-019-09923-2. Epub 2019 Dec 21.
3
Bordetella petrii recovered from chronic pansinusitis in an adult with cystic fibrosis.从一名患有囊性纤维化的成人慢性全鼻窦炎中分离出彼得氏博德特菌。
IDCases. 2015 Sep 26;2(4):97-8. doi: 10.1016/j.idcr.2015.09.004. eCollection 2015.
4
Omega-3 fatty acids for cystic fibrosis.用于治疗囊性纤维化的欧米伽-3脂肪酸。
Cochrane Database Syst Rev. 2016 Jan 5;2016(1):CD002201. doi: 10.1002/14651858.CD002201.pub5.
5
Effects of gender and age at diagnosis on disease progression in long-term survivors of cystic fibrosis.性别和诊断时年龄对囊性纤维化长期生存者疾病进展的影响。
Am J Respir Crit Care Med. 2010 Sep 1;182(5):614-26. doi: 10.1164/rccm.201001-0092OC. Epub 2010 May 6.
6
Genetic and clinical features of patients with cystic fibrosis diagnosed after the age of 16 years.16岁以后确诊的囊性纤维化患者的遗传和临床特征。
Thorax. 1995 Dec;50(12):1301-4. doi: 10.1136/thx.50.12.1301.
7
Cystic fibrosis in adolescents and adults.青少年及成人的囊性纤维化
Thorax. 1987 Jul;42(7):526-32. doi: 10.1136/thx.42.7.526.
8
The epidemiology of Pseudomonas cepacia in patients with cystic fibrosis.囊性纤维化患者中洋葱伯克霍尔德菌的流行病学。
Eur J Epidemiol. 1987 Dec;3(4):336-42. doi: 10.1007/BF00145642.
9
Acute presentation of cystic fibrosis in an adult.一名成年人的囊性纤维化急性表现。
Postgrad Med J. 1989 Jul;65(765):471-2. doi: 10.1136/pgmj.65.765.471.
10
Cystic fibrosis in a 70 year old woman.一名70岁女性的囊性纤维化
Thorax. 1992 Mar;47(3):202-3. doi: 10.1136/thx.47.3.202.
本文引用的文献
1
Effect of age, sex, and cystic fibrosis on the sodium and potassium content of human sweat.年龄、性别和囊性纤维化对人汗液中钠和钾含量的影响。
Pediatrics. 1962 Aug;30:172-9.
2
Fibrocystic disease of the pancreas in a man aged 46.一名46岁男性的胰腺纤维囊性疾病。
Lancet. 1960 Feb 13;1(7120):365-7. doi: 10.1016/s0140-6736(60)90289-0.
3
Mucoviscidosis as a factor in chronic lung disease in adults.黏液黏稠病作为成人慢性肺病的一个因素。
Lancet. 1960 Sep 3;2(7149):514-5. doi: 10.1016/s0140-6736(60)91542-7.
4
Pancreatic cystic fibrosis in an adult.成人胰腺囊性纤维化
JAMA. 1962 Jul 7;181:31-4. doi: 10.1001/jama.1962.03050270033006.
5
'Sweat test' results in normal persons of different ages compared with families with fibrocystic disease of the pancreas.与胰腺纤维囊性病家族相比，不同年龄正常人的“汗液试验”结果。
Arch Dis Child. 1960 Dec;35(184):581-7. doi: 10.1136/adc.35.184.581.
6
A comparison of sweat chlorides and intestinal fat absorption in chronic obstructive pulmonary emphysema and fibrocystic disease of the pancreas.慢性阻塞性肺气肿与胰腺纤维囊性疾病中汗液氯化物及肠道脂肪吸收的比较。
N Engl J Med. 1959 May 7;260(19):951-7. doi: 10.1056/NEJM195905072601901.
7
8
A 69-year-old man with chronic obstructive pulmonary disease, pancreatic insufficiency and elevated sweat electrolytes.一名69岁男性，患有慢性阻塞性肺疾病、胰腺功能不全且汗液电解质升高。
Acta Med Scand. 1981;209(1-2):141-3. doi: 10.1111/j.0954-6820.1981.tb11568.x.
9
Sweat tests to diagnose cystic fibrosis in adults.用于诊断成人囊性纤维化的汗液测试。
Br Med J (Clin Res Ed). 1983 Apr 30;286(6375):1381-3. doi: 10.1136/bmj.286.6375.1381.
10
Obstructive azoospermia as a diagnostic criterion for the cystic fibrosis syndrome.梗阻性无精子症作为囊性纤维化综合征的诊断标准。
Lancet. 1982 Jun 19;1(8286):1401-4. doi: 10.1016/s0140-6736(82)92512-0.
Zotero 插件