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老年女性复发性宫颈癌管理的多模态治疗方法:病例报告

A Multimodality Treatment Approach for the Management of Recurrent Cervical Cancer in an Elderly Female Patient: A Case Report.

作者信息

Jules Manishimwe, Rahul Neha, Weerarathna Induni N, Luharia Anurag

机构信息

Radiation Therapy, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

Radiation Oncology, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

出版信息

Cureus. 2024 Jul 26;16(7):e65424. doi: 10.7759/cureus.65424. eCollection 2024 Jul.

DOI:10.7759/cureus.65424
PMID:39184781
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11344611/
Abstract

Squamous cells in the cervix can develop into a type of cervical cancer. Cervical squamous cells are the cells that line the outside of the cervix. These thin, flat cells have a striking resemblance to fish scales under a microscope. Squamous cell carcinomas (SCCs) are the most common type of cervical cancer. We report the case of a 60-year-old woman with SCC devoid of a family history of cancer or related diseases. Following a biopsy confirming SCC, the patient's contrast-enhanced computed tomography scan revealed a somewhat enlarged cervix along with a white discharge per vagina. The patient underwent a Wertheim hysterectomy and was diagnosed with microinvasive SCC, adenomyosis, and negative lymph nodes. Two years after being free from disease, the issue reappeared even with routine follow-ups. The patient underwent six rounds of chemotherapy, followed by chemoradiation and interstitial brachytherapy. The multimodality therapy method applied to an aged female patient experiencing recurrent SCC of the cervix is demonstrated in this case study. It underlines how crucial regular follow-ups and multimodal therapy are to control recurrent cervical cancer.

摘要

子宫颈中的鳞状细胞会发展成一种子宫颈癌。子宫颈鳞状细胞是排列在子宫颈外侧的细胞。这些薄而扁平的细胞在显微镜下与鱼鳞极为相似。鳞状细胞癌(SCC)是最常见的子宫颈癌类型。我们报告了一例60岁患有鳞状细胞癌的女性病例,该患者没有癌症或相关疾病的家族史。活检确诊为鳞状细胞癌后,患者的增强计算机断层扫描显示子宫颈略有增大,伴有阴道白色分泌物。患者接受了根治性子宫切除术,被诊断为微浸润性鳞状细胞癌、子宫腺肌病,且淋巴结阴性。在无病两年后,即使进行了常规随访,问题还是再次出现。患者接受了六轮化疗,随后进行了放化疗和间质近距离放疗。本病例研究展示了应用于一名患有复发性子宫颈鳞状细胞癌老年女性患者的多模态治疗方法。它强调了定期随访和多模态治疗对于控制复发性子宫颈癌的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfe6/11344611/06ed48318935/cureus-0016-00000065424-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfe6/11344611/57b49e904f63/cureus-0016-00000065424-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfe6/11344611/35a9fc13326c/cureus-0016-00000065424-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfe6/11344611/349ecbba2c62/cureus-0016-00000065424-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfe6/11344611/06ed48318935/cureus-0016-00000065424-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfe6/11344611/57b49e904f63/cureus-0016-00000065424-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfe6/11344611/35a9fc13326c/cureus-0016-00000065424-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfe6/11344611/349ecbba2c62/cureus-0016-00000065424-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfe6/11344611/06ed48318935/cureus-0016-00000065424-i06.jpg

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本文引用的文献

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A Case for the Conservative Management of Stage IA Cervical Cancer.IA期宫颈癌保守治疗的病例分析
Cancers (Basel). 2023 Oct 19;15(20):5051. doi: 10.3390/cancers15205051.
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ESGO/ESTRO quality indicators for radiation therapy of cervical cancer.ESGO/ESTRO 宫颈癌放射治疗质量指标。
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Recognizing Gynecological Cancer in Primary Care: Risk Factors, Red Flags, and Referrals.初级保健中的妇科癌症识别:风险因素、警示信号和转诊。
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Cervical cancer screening in developing countries at a crossroad: Emerging technologies and policy choices.发展中国家宫颈癌筛查处于十字路口:新兴技术与政策选择
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