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基于人工智能的移动应用程序的开发和测试,以实现印度北方邦的白内障积压清零。

Development and Testing of Artificial Intelligence-Based Mobile Application to Achieve Cataract Backlog-Free Status in Uttar Pradesh, India.

机构信息

Institute for Global Public Health, University of Manitoba, R070 Med Rehab Bldg, 771 McDermot Avenue, Winnipeg, MB R3E 0T6, Canada.

Institute for Global Public Health, University of Manitoba, R070 Med Rehab Bldg, 771 McDermot Avenue, Winnipeg, MB R3E 0T6, Canada; Government of India, UT of Ladakh.

出版信息

Asia Pac J Ophthalmol (Phila). 2024 Sep-Oct;13(5):100094. doi: 10.1016/j.apjo.2024.100094. Epub 2024 Aug 24.

Abstract

BACKGROUND

Uttar Pradesh (UP), the most populous state in India, has about 36 million people aged 50 years or older, spread across more than 100,000 villages. Among them, an estimated 3.5 million suffer from visual impairments, including blindness due to untreated cataracts. To achieve cataract backlog-free status, UP is required to screen this population at the community level and provide treatment to those suffering from cataracts. We envisioned an AI-powered primary screening app utilizing eye images, deployable to frontline health workers for community-level screening. This paper outlines insights gained from developing the AI mobile app "Roshni" for cataract screening.

METHOD

The AI-based cataract classification model was developed using 13,633 eye images and finalized after three stages of experiments, detecting cataracts in images focused on the eye, iris, and pupil. Overall, 155 experiments were conducted using multiple deep learning algorithms, including ResNet50, ResNet101, YOLOv5, EfficientNetV2, and InceptionV3. We established a minimum threshold of 90 % specificity and sensitivity to ensure the algorithm's suitability for field use.

RESULTS

The cataract detection model for eye-focused images achieved 51.9 % sensitivity and 87.6 % specificity, while the model for iris-focused images, using a good/bad iris filter, achieved 52.4 % sensitivity and 93.3 % specificity. The classification model for segmented-pupil images, employing a good/bad pupil filter with UNet-based semantic segmentation model and EfficientNetV2, yielded 96 % sensitivity and 97 % specificity. Field testing with 302 beneficiaries (604 images) showed an overall sensitivity of 86.6 %, specificity of 93.3 %, positive predictive value of 58.4 %, and negative predictive value of 98.5 %.

CONCLUSION

This paper details the development of an AI mobile app designed to facilitate community screening for cataracts by frontline health workers.

摘要

背景

印度人口最多的北方邦(Uttar Pradesh,简称 UP)拥有约 3600 万 50 岁以上的人口,分布在 10 多万个村庄。其中,估计有 350 万人患有视力障碍,包括因未治疗的白内障导致的失明。为了实现白内障清零状态,北方邦需要在社区层面筛查这部分人群,并为白内障患者提供治疗。我们设想了一个由人工智能驱动的初级筛查应用程序,该程序使用眼部图像,可供一线卫生工作者在社区层面进行筛查。本文介绍了为白内障筛查开发人工智能移动应用程序“Roshni”所获得的见解。

方法

使用 13633 张眼部图像开发了基于人工智能的白内障分类模型,并在经过三个阶段的实验后完成,实验分别检测眼部、虹膜和瞳孔图像中的白内障。总共使用了包括 ResNet50、ResNet101、YOLOv5、EfficientNetV2 和 InceptionV3 在内的多种深度学习算法进行了 155 次实验。我们建立了 90%的特异性和敏感性最低阈值,以确保算法适合现场使用。

结果

针对眼部聚焦图像的白内障检测模型实现了 51.9%的敏感性和 87.6%的特异性,而使用良好/不良虹膜滤波器的针对虹膜聚焦图像的模型则实现了 52.4%的敏感性和 93.3%的特异性。使用 UNet 基于语义分割模型和 EfficientNetV2 的良好/不良瞳孔滤波器对分割瞳孔图像的分类模型,获得了 96%的敏感性和 97%的特异性。对 302 名受益人(604 张图像)进行现场测试,总体敏感性为 86.6%,特异性为 93.3%,阳性预测值为 58.4%,阴性预测值为 98.5%。

结论

本文详细介绍了一种人工智能移动应用程序的开发,旨在方便一线卫生工作者进行社区白内障筛查。

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