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反思国际抗核抗体共识 (ICAP) 十年:第 7 届 ICAP 研讨会视角下的成就与挑战。

Reflecting on a decade of the international consensus on ANA patterns (ICAP): Accomplishments and challenges from the perspective of the 7th ICAP workshop.

机构信息

Rheumatology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil; Immunology Division, Fleury Medicine and Health Laboratories, São Paulo, Brazil.

Department of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria.

出版信息

Autoimmun Rev. 2024 Sep;23(9):103608. doi: 10.1016/j.autrev.2024.103608. Epub 2024 Aug 24.

Abstract

The International Consensus on ANA Patterns (ICAP) is an ongoing international initiative dedicated to harmonizing technical and interpretation aspects of the HEp-2 IFA test. Comprised of internationally recognized experts in autoimmunity and HEp-2 IFA testing, ICAP has operated for the last 10 years by promoting accurate reading, interpretation, and reporting of HEp-2 IFA images by professionals involved in various areas related to autoimmune diseases, such as clinical diagnostic laboratories, academic research, IVD industry, and patient care. ICAP operates through continuous information exchange with the international community and encourages the participation of younger experts from all over the world. The 7th ICAP workshop has addressed several aspects that originated from this interaction with the international community and has effectively established objective goals and tasks to be delivered over the next two years. Some of these are outlined in this article, including the planning of three audio-visual educational modules to be posted at the www.anapattern.org website, the classification of two novel HEp-2 IFA patterns, the implementation of a project dedicated to continuously updating the information on the clinical and immunologic relevance of the HEp-2 IFA patterns, and the launch of two additional branches of the HEp-2 Clinical and Immunological (HEp-2 CIC) project.

摘要

国际抗核抗体图谱共识 (ICAP) 是一项正在进行的国际倡议,致力于协调 HEp-2IFA 检测的技术和解释方面。该倡议由在自身免疫和 HEp-2IFA 检测方面具有国际公认专业知识的专家组成,在过去的 10 年里,通过促进与自身免疫性疾病相关的各个领域(如临床诊断实验室、学术研究、体外诊断行业和患者护理)的专业人员准确读取、解释和报告 HEp-2IFA 图像,ICAP 一直在运作。ICAP 通过与国际社会不断交流信息,并鼓励来自世界各地的年轻专家参与。第 7 届 ICAP 研讨会讨论了一些源自与国际社会互动的方面,并有效地为未来两年设定了要实现的客观目标和任务。本文概述了其中的一些内容,包括在 www.anapattern.org 网站上发布三个视听教育模块的计划、两种新型 HEp-2IFA 图谱的分类、实施一个致力于不断更新 HEp-2IFA 图谱的临床和免疫学相关性信息的项目,以及启动两个额外的 HEp-2 临床和免疫学(HEp-2CIC)项目分支。

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