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病例报告:创伤后眼内炎中的新出现物种:

Case report: Emerging species in post-traumatic endophthalmitis: .

作者信息

Hu Jiezhong, Huang Chunling, Li Jingyi, Fang Caixia, Li Jiali, Feng Songfu

机构信息

Department of Ophthalmology, Houjie Hospital, Dongguan, China.

Department of Ophthalmology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.

出版信息

Front Med (Lausanne). 2024 Aug 13;11:1406277. doi: 10.3389/fmed.2024.1406277. eCollection 2024.

DOI:10.3389/fmed.2024.1406277
PMID:39193018
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11347439/
Abstract

is an uncommon cause of endophthalmitis. This case report describes a 40-year-old male admitted with pain, redness, and vision loss in his right eye after an open globe injury by a steel fragment. Clinical assessment confirmed post-traumatic endophthalmitis with an intraocular foreign body. The patient underwent a vitreous biopsy, lensectomy, vitrectomy, and intravitreal antibiotics, followed by laser photocoagulation and foreign body extraction via the pars plana. Acinetobacter johnsonii was isolated from the vitreous culture. A combination of vancomycin, levofloxacin and ceftazidime was administered, leading to reduced infection and inflammation. Postoperatively at one month, the patients' best-corrected visual acuity had improved to 20/63. The anterior segment exhibited no inflammation, the vitreous cavity was clear, and the retina with hemorrhage and laser treatment remained stable. The one-year follow-up confirmed the continued stability of the ocular condition. , a rare cause of endophthalmitis often linked to trauma or surgery, should be recognized as a possible pathogen in post-traumatic endophthalmitis cases, meriting clinical consideration.

摘要

是眼内炎的一种罕见病因。本病例报告描述了一名40岁男性,在被钢碎片开放性眼球损伤后,因右眼疼痛、发红和视力丧失入院。临床评估证实为创伤后眼内炎伴眼内异物。患者接受了玻璃体活检、晶状体切除术、玻璃体切除术和玻璃体内抗生素治疗,随后进行激光光凝和经睫状体扁平部异物取出术。从玻璃体培养物中分离出约翰逊不动杆菌。给予万古霉素、左氧氟沙星和头孢他啶联合治疗,导致感染和炎症减轻。术后1个月,患者的最佳矫正视力提高到20/63。眼前节无炎症,玻璃体腔清晰,视网膜有出血且激光治疗后保持稳定。1年随访证实眼部状况持续稳定。 ,一种常与创伤或手术相关的眼内炎罕见病因,应被视为创伤后眼内炎病例的可能病原体,值得临床考虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bda/11347439/729cf2177b4f/fmed-11-1406277-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bda/11347439/678077f4db28/fmed-11-1406277-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bda/11347439/729cf2177b4f/fmed-11-1406277-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bda/11347439/678077f4db28/fmed-11-1406277-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bda/11347439/729cf2177b4f/fmed-11-1406277-g002.jpg

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本文引用的文献

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T-shaped pars plana scleral incision to remove large intraocular foreign body.采用T形巩膜平坦部切口取出眼内大异物。
Front Med (Lausanne). 2024 May 14;11:1399321. doi: 10.3389/fmed.2024.1399321. eCollection 2024.
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Differential development of antibiotic resistance and virulence between species.种间抗生素耐药性和毒力的差异发展。
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Antimicrobial resistance in ocular infection: A review.眼部感染中的抗菌药物耐药性:综述。
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Sympathetic Ophthalmia after Vitreoretinal Surgery without Antecedent History of Trauma: A Systematic Review and Meta-Analysis.玻璃体视网膜手术后无既往创伤史的交感性眼炎:一项系统评价和荟萃分析
J Clin Med. 2023 Mar 16;12(6):2316. doi: 10.3390/jcm12062316.
5
Broad-Spectrum Antimicrobial Activity of Oftasecur and Visuprime Ophthalmic Solutions.奥夫他舒和维舒普明眼科溶液的广谱抗菌活性。
Microorganisms. 2023 Feb 17;11(2):503. doi: 10.3390/microorganisms11020503.
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[Chinese expert consensus on the prophylaxis and management of traumatic infectious endophthalmitis (2023)].《外伤性感染性眼内炎防治专家共识(2023年版)》
Zhonghua Yan Ke Za Zhi. 2023 Feb 11;59(2):90-95. doi: 10.3760/cma.j.cn112142-20221018-00521.
7
Emerging Antibiotic Resistance Patterns Affect Visual Outcome Treating Acute Endophthalmitis.新出现的抗生素耐药模式影响急性眼内炎的视觉治疗效果。
Antibiotics (Basel). 2022 Jun 23;11(7):843. doi: 10.3390/antibiotics11070843.
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