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选择性激光熔化制备的3D钛多孔表面与口腔细菌之间的相互作用——一篇综述

The Interaction between Oral Bacteria and 3D Titanium Porous Surfaces Produced by Selective Laser Melting-A Narrative Review.

作者信息

Dotta Tatiane Cristina, D'Ercole Simonetta, Iezzi Giovanna, Pedrazzi Vinicius, Galo Rodrigo, Petrini Morena

机构信息

Department of Dental Materials and Prosthodontics, Ribeirão Preto School of Dentistry, University of São Paulo, São Paulo 14040-904, Brazil.

Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, 66100 Chieti, Italy.

出版信息

Biomimetics (Basel). 2024 Jul 29;9(8):461. doi: 10.3390/biomimetics9080461.

Abstract

The interaction between oral bacteria and dental implant surfaces is a critical factor in the success and longevity of dental implants. With advancements in additive manufacturing technologies, selective laser melting (SLM) has emerged as a prominent method for producing titanium implants with highly controlled microstructures and porosities. These 3D printed titanium surfaces offer significant benefits, such as enhanced osseointegration and improved mechanical properties. However, the same surface features that promote bone cell attachment and proliferation may also provide favorable conditions for bacterial adhesion and biofilm formation. Understanding the dynamics of these interactions is essential for developing implant surfaces that can effectively resist bacterial colonization while promoting tissue integration. This narrative review explores the complex interplay between oral bacteria and SLM-produced titanium porous surfaces, examining current research findings and potential strategies for optimizing implant design to mitigate the risks of infection and ensure successful clinical outcomes.

摘要

口腔细菌与牙种植体表面之间的相互作用是牙种植体成功及长期使用的关键因素。随着增材制造技术的进步,选择性激光熔化(SLM)已成为一种用于生产具有高度可控微观结构和孔隙率的钛种植体的突出方法。这些3D打印的钛表面具有显著优势,如增强骨整合和改善机械性能。然而,促进骨细胞附着和增殖的相同表面特征也可能为细菌黏附和生物膜形成提供有利条件。了解这些相互作用的动态过程对于开发能够有效抵抗细菌定植同时促进组织整合的种植体表面至关重要。本叙述性综述探讨了口腔细菌与SLM制造的钛多孔表面之间的复杂相互作用,研究了当前的研究结果以及优化种植体设计以降低感染风险并确保临床成功结果的潜在策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/549d/11351682/72e2c8d2444e/biomimetics-09-00461-g001.jpg

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