Department of Mathematics and Computer Science, Transilvania University of Brasov, 500036 Brașov, Romania.
Biosensors (Basel). 2024 Aug 7;14(8):380. doi: 10.3390/bios14080380.
The dynamic monitoring of biomolecules that are part of cell membranes generally constitutes a challenge. Electrochemiluminescence (ECL) biosensor assemblies provide clear advantages concerning microscopic imaging. Therefore, this paper proposes and analyzes a quantum dots-based biosensor assembly. Thus, particular attention is granted to biomolecules that are part of cell membranes. Additionally, this paper describes and analyzes a quantum dots-based biosensor assembly, which is used to implement a fully functional color ECL visualization system that allows for cellular and biomolecular structures to be accurately visualized. The related nano-emitter allows the implementation of real-time bioimaging scenarios. Consequently, the proposed approach is thoroughly evaluated relative to the time-dependent evolution of biomolecules. It has been demonstrated that traditionally problematic structures, like the biomolecules that are part of cell membranes, can be studied and monitored relative to their time-dependent dynamic evolution using the proposed solution. The reported research process has been conducted in the realm of cooperation with a specialized biomedical engineering company, and the described results are expected to substantially support a better understanding of the biomolecules' time-dependent dynamic evolution.
细胞膜中生物分子的动态监测通常是一个挑战。电化学发光（ECL）生物传感器组件在微观成像方面具有明显的优势。因此，本文提出并分析了一种基于量子点的生物传感器组件。因此，特别关注细胞膜中的生物分子。此外，本文还描述和分析了一种基于量子点的生物传感器组件，该组件用于实现全功能彩色 ECL 可视化系统，该系统能够精确地可视化细胞和生物分子结构。相关的纳米发射器允许实现实时生物成像场景。因此，相对于生物分子的时变演化，对所提出的方法进行了彻底的评估。已经证明，使用所提出的解决方案可以研究和监测传统上有问题的结构，例如细胞膜中的生物分子，以及它们的时变动态演化。所报告的研究过程是在与专门的生物医学工程公司合作的范围内进行的，所描述的结果有望大大支持对生物分子时变动态演化的更好理解。
