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探索腰椎椎间孔狭窄症治疗与管理中疼痛缓解的途径:文献综述

Exploring Pathways for Pain Relief in Treatment and Management of Lumbar Foraminal Stenosis: A Review of the Literature.

作者信息

Nurmukhametov Renat, De Jesus Encarnacion Ramirez Manuel, Dosanov Medet, Medetbek Abakirov, Kudryakov Stepan, Reyes Soto Gervith, Ponce Espinoza Claudia B, Mukengeshay Jeff Natalaja, Mpoyi Cherubin Tshiunza, Nikolenko Vladimir, Gushcha Artem, Sharif Salman, Montemurro Nicola

机构信息

2nd National Clinical Centre, Federal State Budgetary Research Institution, Russian Research Center of Surgery Named after Academician B.V. Petrovsky, 103274 Moscow, Russia.

Department of Neurosurgery, Russian People's Friendship University, 121359 Moscow, Russia.

出版信息

Brain Sci. 2024 Jul 24;14(8):740. doi: 10.3390/brainsci14080740.

DOI:10.3390/brainsci14080740
PMID:39199435
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11352478/
Abstract

BACKGROUND

Lumbar foraminal stenosis (LFS) involves the narrowing of neural foramina, leading to nerve compression, significant lower back pain and radiculopathy, particularly in the aging population. Management includes physical therapy, medications and potentially invasive surgeries such as foraminotomy. Advances in diagnostic and treatment strategies are essential due to LFS's complexity and prevalence, which underscores the importance of a multidisciplinary approach in optimizing patient outcomes.

METHOD

This literature review on LFS employed a systematic methodology to gather and synthesize recent scientific data. A comprehensive search was conducted across PubMed, Scopus and Cochrane Library databases using specific keywords related to LFS. The search, restricted to English language articles from 1 January 2000 to 31 December 2023, focused on peer-reviewed articles, clinical trials and reviews. Due to the heterogeneity among the studies, data were qualitatively synthesized into themes related to diagnosis, treatment and pathophysiology.

RESULTS

This literature review on LFS analyzed 972 articles initially identified, from which 540 remained after removing duplicates. Following a rigorous screening process, 20 peer-reviewed articles met the inclusion criteria and were reviewed. These studies primarily focused on evaluating the diagnostic accuracy, treatment efficacy and pathophysiological insights into LFS.

CONCLUSION

The comprehensive review underscores the necessity for precise diagnostic and management strategies for LFS, highlighting the role of a multidisciplinary approach and the utility of a unified classification system in enhancing patient outcomes in the face of this condition's increasing prevalence.

摘要

背景

腰椎椎间孔狭窄(LFS)涉及神经孔变窄,导致神经受压、严重的下背部疼痛和神经根病,在老年人群中尤为常见。治疗方法包括物理治疗、药物治疗以及可能的侵入性手术,如椎间孔切开术。由于LFS的复杂性和患病率,诊断和治疗策略的进展至关重要,这凸显了多学科方法在优化患者治疗效果方面的重要性。

方法

本关于LFS的文献综述采用系统方法收集和综合近期科学数据。使用与LFS相关的特定关键词,在PubMed、Scopus和Cochrane图书馆数据库中进行了全面搜索。搜索仅限于2000年1月1日至2023年12月31日的英文文章,重点是同行评审文章、临床试验和综述。由于研究之间存在异质性,数据被定性综合为与诊断、治疗和病理生理学相关的主题。

结果

本关于LFS的文献综述分析了最初识别出的972篇文章,去除重复项后还剩540篇。经过严格的筛选过程,20篇同行评审文章符合纳入标准并进行了评审。这些研究主要集中在评估LFS的诊断准确性、治疗效果和病理生理学见解。

结论

全面综述强调了LFS精确诊断和管理策略的必要性,突出了多学科方法的作用以及统一分类系统在面对这种疾病患病率不断上升的情况下提高患者治疗效果的实用性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a63b/11352478/3abe9c01969d/brainsci-14-00740-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a63b/11352478/f5609132c296/brainsci-14-00740-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a63b/11352478/7b6d3f8380ba/brainsci-14-00740-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a63b/11352478/5f0a92f2ce2e/brainsci-14-00740-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a63b/11352478/3abe9c01969d/brainsci-14-00740-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a63b/11352478/f5609132c296/brainsci-14-00740-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a63b/11352478/7b6d3f8380ba/brainsci-14-00740-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a63b/11352478/5f0a92f2ce2e/brainsci-14-00740-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a63b/11352478/3abe9c01969d/brainsci-14-00740-g004.jpg

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