Tamaš Olivera, Kovačević Marija, Dobrodolac Aleksandra, Rašuo Bosnić Nada, Tot Šari Žužana, Despenić Livija, Vécsei László, Bencsik Krisztina, Pekmezović Tatjana, Drulović Jelena
Neurology Clinic, University Clinical Center of Serbia, 11000 Beograd, Serbia.
Medical Faculty, University of Belgrade, 11000 Belgrade, Serbia.
Brain Sci. 2024 Aug 17;14(8):825. doi: 10.3390/brainsci14080825.
Fatigue is one of the most frequent complaints of patients with multiple sclerosis (MS). The Fatigue Impact Scale (FIS), one of the 30 available fatigue questionnaires, is commonly applied because it evaluates multidimensional aspects of fatigue. The chief objectives of this study were to validate FIS and evaluate the psychometric properties of MS patients in Serbia. One hundred and twenty-one (121) MS patients and one hundred and twenty-two (122) age-, gender- and education-matched healthy control (HC) subjects completed the FIS and the Beck Depression Inventory. Internal consistency of the FIS subscales was determined using Cronbach's Alpha Coefficient. Test/retest reliability with an intra-class correlation coefficient (ICC) for each FIS subscale was performed. The total FIS score and subscale scores showed statistically significant differences between the MS patients and the HC subjects in both FIS sessions. Cronbach's Alpha was 0.966. All ICCs were statistically significant ( < 0.05). The Serbian version of this instrument may be useful as a clinical measure for fatigue and functionality in patients with MS.
疲劳是多发性硬化症（MS）患者最常见的主诉之一。疲劳影响量表（FIS）是现有的30种疲劳调查问卷之一，因其能评估疲劳的多维度方面而被广泛应用。本研究的主要目的是验证FIS，并评估塞尔维亚MS患者的心理测量学特性。121名MS患者和122名年龄、性别和教育程度相匹配的健康对照（HC）受试者完成了FIS和贝克抑郁量表。使用克朗巴哈α系数确定FIS子量表的内部一致性。对每个FIS子量表进行了组内相关系数（ICC）的重测信度分析。在两次FIS测试中，MS患者和HC受试者的FIS总分及子量表得分均存在统计学显著差异。克朗巴哈α系数为0.966。所有ICC均具有统计学显著性（<0.05）。该工具的塞尔维亚语版本可能作为MS患者疲劳和功能的临床测量工具。
