Department of Neurology, Albert Szent-Györgyi Clinical Centre, University of Szeged, 6 Semmelweis u., 6725, Szeged, Hungary.
Qual Life Res. 2011 Mar;20(2):301-6. doi: 10.1007/s11136-010-9749-7. Epub 2010 Sep 24.
Fatigue is one of the most frequent complaints of patients with multiple sclerosis (MS). The Fatigue Impact Scale (FIS), one of the 30 available fatigue questionnaires, is commonly applied because it evaluates multidimensional aspects of fatigue. The main purposes of this study were to test the validity, test-retest reliability, and internal consistency of the Hungarian version of the FIS.
One hundred and eleven MS patients and 85 healthy control (HC) subjects completed the FIS and the Beck Depression Inventory, a large majority of them on two occasions, 3 months apart.
The total FIS score and subscale scores differed statistically between the MS patients and the HC subjects in both FIS sessions. In the test-retest reliability assessment, statistically, the intraclass correlation coefficients were high in both the MS and HC groups. Cronbach's alpha values were also notably high.
The results of this study indicate that the FIS can be regarded as a valid and reliable scale with which to improve our understanding of the impact of fatigue on the health-related quality of life in MS patients without severe disability.
疲劳是多发性硬化症（MS）患者最常见的抱怨之一。疲劳影响量表（FIS）是 30 种可用的疲劳问卷之一，因其评估疲劳的多维方面而被广泛应用。本研究的主要目的是检验 FIS 的匈牙利文版本的效度、重测信度和内部一致性。
111 名 MS 患者和 85 名健康对照组（HC）受试者完成了 FIS 和贝克抑郁量表，他们中的绝大多数在 3 个月的间隔时间内完成了两次测试。
在两次 FIS 测试中，MS 患者和 HC 受试者的 FIS 总分和子量表评分在统计学上存在显著差异。在重测信度评估中，MS 和 HC 组的组内相关系数均较高。克朗巴赫的α值也非常高。
本研究的结果表明，FIS 可以被视为一种有效的、可靠的量表，它可以帮助我们更好地理解疲劳对无严重残疾的 MS 患者健康相关生活质量的影响。
