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全基因组关联研究(GWAS)和多组学全基因组关联研究(mGWAS)在畜禽育种中的应用。

Application of GWAS and mGWAS in Livestock and Poultry Breeding.

作者信息

Ren Jing, Gao Zhendong, Lu Ying, Li Mengfei, Hong Jieyun, Wu Jiao, Wu Dongwang, Deng Weidong, Xi Dongmei, Chong Yuqing

机构信息

Key Laboratory of Animal Genetics, Breeding and Reproduction in the Plateau Mountainous Region, Ministry of Education, Guizhou University, Guiyang 550025, China.

Yunnan Provincial Key Laboratory of Animal Nutrition and Feed, Faculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.

出版信息

Animals (Basel). 2024 Aug 16;14(16):2382. doi: 10.3390/ani14162382.

Abstract

In recent years, genome-wide association studies (GWAS) and metabolome genome-wide association studies (mGWAS) have emerged as crucial methods for investigating complex traits in animals and plants. These have played pivotal roles in research on livestock and poultry breeding, facilitating a deeper understanding of genetic diversity, the relationship between genes, and genetic bases in livestock and poultry. This article provides a review of the applications of GWAS and mGWAS in animal genetic breeding, aiming to offer reference and inspiration for relevant researchers, promote innovation in animal genetic improvement and breeding methods, and contribute to the sustainable development of animal husbandry.

摘要

近年来,全基因组关联研究(GWAS)和代谢组全基因组关联研究(mGWAS)已成为研究动植物复杂性状的关键方法。这些方法在畜禽育种研究中发挥了关键作用,有助于更深入地了解畜禽的遗传多样性、基因之间的关系以及遗传基础。本文综述了GWAS和mGWAS在动物遗传育种中的应用,旨在为相关研究人员提供参考和启示,推动动物遗传改良和育种方法的创新,为畜牧业的可持续发展做出贡献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b2c/11350712/8d86c2f5f7f1/animals-14-02382-g001.jpg

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