Zachariades N, Papanicolaou S, Xypolyta A, Constantinidis I
Int J Oral Surg. 1985 Apr;14(2):138-45. doi: 10.1016/s0300-9785(85)80085-5.
Cherubism is a benign, hereditary giant cell lesion of the jaws, that appears in children as a bilateral painless swelling, between the ages of 2 and 5 years and progresses until puberty, when it spontaneously regresses. It normally requires no treatment. We had the chance to operate on a 5-year-old boy with cherubism 8 years ago, and used homogenous bone grafts to replace the diseased tissue to avoid pathological fracture of the mandible. Since then we have been following the patient, witnessing the gradual involvement of other sites in the jaws and the displacement of teeth and tooth germs.
颌骨肥大症是一种发生于颌骨的良性遗传性巨细胞病变，在2至5岁儿童中表现为双侧无痛性肿胀，持续发展至青春期后自行消退。通常无需治疗。8年前我们有机会为一名患有颌骨肥大症的5岁男孩进行手术，使用同种异体骨移植来替代病变组织，以避免下颌骨病理性骨折。从那时起我们一直在跟踪该患者，见证了颌骨其他部位逐渐受累以及牙齿和牙胚移位的过程。
