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优化分类和连续分类多性状混合的基因组亲本选择。

Optimizing Genomic Parental Selection for Categorical and Continuous-Categorical Multi-Trait Mixtures.

机构信息

International Maize and Wheat Improvement Center (CIMMYT), Km 45, Carretera México-Veracruz, Texcoco CP 52640, Estado de México, Mexico.

Colegio de Postgraduados, Montecillos CP 56230, Estado de México, Mexico.

出版信息

Genes (Basel). 2024 Jul 29;15(8):995. doi: 10.3390/genes15080995.

DOI:10.3390/genes15080995
PMID:39202356
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11353433/
Abstract

This study presents a novel approach for the optimization of genomic parental selection in breeding programs involving categorical and continuous-categorical multi-trait mixtures (CMs and CCMMs). Utilizing the Bayesian decision theory (BDT) and latent trait models within a multivariate normal distribution framework, we address the complexities of selecting new parental lines across ordinal and continuous traits for breeding. Our methodology enhances precision and flexibility in genetic selection, validated through extensive simulations. This unified approach presents significant potential for the advancement of genetic improvements in diverse breeding contexts, underscoring the importance of integrating both categorical and continuous traits in genomic selection frameworks.

摘要

本研究提出了一种新的方法,用于优化涉及分类和连续分类多性状混合物(CM 和 CCMM)的育种计划中的基因组亲本选择。本研究利用贝叶斯决策理论(BDT)和潜在特征模型,在多元正态分布框架内,解决了在分类和连续性状方面选择新亲本系的复杂性。我们的方法通过广泛的模拟验证了提高遗传选择精度和灵活性的方法。这种统一的方法为不同育种背景下的遗传改良提供了重要的潜力,强调了在基因组选择框架中整合分类和连续性状的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21b/11353433/730382c472b5/genes-15-00995-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21b/11353433/85126ef258e4/genes-15-00995-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21b/11353433/0d2a91e3b629/genes-15-00995-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21b/11353433/84f8f6f3c207/genes-15-00995-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21b/11353433/c358c3e1db26/genes-15-00995-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21b/11353433/70d8f30ff832/genes-15-00995-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21b/11353433/277d7a303e95/genes-15-00995-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21b/11353433/730382c472b5/genes-15-00995-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21b/11353433/85126ef258e4/genes-15-00995-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21b/11353433/0d2a91e3b629/genes-15-00995-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21b/11353433/84f8f6f3c207/genes-15-00995-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21b/11353433/c358c3e1db26/genes-15-00995-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21b/11353433/70d8f30ff832/genes-15-00995-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21b/11353433/277d7a303e95/genes-15-00995-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21b/11353433/730382c472b5/genes-15-00995-g007.jpg

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本文引用的文献

1
A Bayesian optimization R package for multitrait parental selection.贝叶斯优化 R 包在多性状亲本品系选择中的应用。
Plant Genome. 2024 Jun;17(2):e20433. doi: 10.1002/tpg2.20433. Epub 2024 Feb 22.
2
Multitrait Bayesian shrinkage and variable selection models with the BGLR-R package.多特质贝叶斯收缩和变量选择模型,使用 BGLR-R 包。
Genetics. 2022 Aug 30;222(1). doi: 10.1093/genetics/iyac112.
3
Breeding for adaptation to climate change: genomic selection for drought response in a white spruce multi-site polycross test.适应气候变化的育种:白云杉多地点多系杂交试验中干旱响应的基因组选择
Evol Appl. 2022 Feb 28;15(3):383-402. doi: 10.1111/eva.13348. eCollection 2022 Mar.
4
Predictions from algorithmic modeling result in better decisions than from data modeling for soybean iron deficiency chlorosis.算法模型的预测结果比数据模型更能准确预测大豆缺铁性黄化。
PLoS One. 2021 Jul 9;16(7):e0240948. doi: 10.1371/journal.pone.0240948. eCollection 2021.
5
Application of multi-trait Bayesian decision theory for parental genomic selection.多性状贝叶斯决策理论在亲本基因组选择中的应用。
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6
Combined Multistage Linear Genomic Selection Indices To Predict the Net Genetic Merit in Plant Breeding.用于预测植物育种中净遗传价值的组合多阶段线性基因组选择指数
G3 (Bethesda). 2020 Jun 1;10(6):2087-2101. doi: 10.1534/g3.120.401171.
7
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Evol Appl. 2019 Jun 20;13(1):76-94. doi: 10.1111/eva.12823. eCollection 2020 Jan.
8
A Bayesian Decision Theory Approach for Genomic Selection.一种用于基因组选择的贝叶斯决策理论方法。
G3 (Bethesda). 2018 Aug 30;8(9):3019-3037. doi: 10.1534/g3.118.200430.
9
Genome-wide prediction models that incorporate de novo GWAS are a powerful new tool for tropical rice improvement.整合从头全基因组关联研究(de novo GWAS)的全基因组预测模型是热带水稻改良的一种强大新工具。
Heredity (Edinb). 2016 Apr;116(4):395-408. doi: 10.1038/hdy.2015.113. Epub 2016 Feb 10.
10
GPOPSIM: a simulation tool for whole-genome genetic data.GPOPSIM:一种用于全基因组遗传数据的模拟工具。
BMC Genet. 2015 Feb 5;16(1):10. doi: 10.1186/s12863-015-0173-4.