Antimicrobial Resistance and Genomic Characterization of and Isolated from Retail Chickens in Beijing, China.

Objective species are the main causes of foodborne illness worldwide, posing significant threats to public health. This study aimed to investigate the antibiotic resistance and genomic characterization of / from retail chickens in Beijing. Methods Antimicrobial susceptibility testing was conducted on 126 / isolated from retail chickens in Beijing, following CLSI protocols. Whole genomes of all isolates were sequenced using the Illumina platform. Results More (83.82%) showed multi-drug resistance than (8.62%). Genomic analysis demonstrated 42 sequence types (STs) and 12 clonal complexes (CCs), from which CC828 and CC52 were dominant. , and encoding cytotoxic protein were present spontaneously in most but not found in any isolates. The abundances of antibiotic resistance genes (ARGs) and virulence genes (VGs) in and were significantly different, with ARGs numbered in and VGs in . Conclusions High prevalence of multi-drug resistance and isolated from Beijing chickens were challenging clinical antibiotic usages in the treatment of infection. The surveillance of particular and STs correlated with higher resistance and virulence needs to be strengthened in the future.