Stevanović Jevrosima, Glavinić Uroš, Ristanić Marko, Erjavec Vladimira, Denk Barış, Dolašević Slobodan, Stanimirović Zoran
Department of Biology, Faculty of Veterinary Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Small Animal Clinic, Veterinary Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia.
Pharmaceuticals (Basel). 2024 Aug 9;17(8):1050. doi: 10.3390/ph17081050.
This review aims to present current knowledge on the effects of honey bee products on animals based on in vivo studies, focusing on their application in clinical veterinary practice. Honey's best-proven effectiveness is in treating wounds, including those infected with antibiotic-resistant microorganisms, as evidenced in horses, cats, dogs, mice, and rats. Propolis manifested a healing effect in numerous inflammatory and painful conditions in mice, rats, dogs, and pigs and also helped in oncological cases in mice and rats. Bee venom is best known for its effectiveness in treating neuropathy and arthritis, as shown in dogs, mice, and rats. Besides, bee venom improved reproductive performance, immune response, and general health in rabbits, chickens, and pigs. Pollen was effective in stimulating growth and improving intestinal microflora in chickens. Royal jelly might be used in the management of animal reproduction due to its efficiency in improving fertility, as shown in rats, rabbits, and mice. Drone larvae are primarily valued for their androgenic effects and stimulation of reproductive function, as evidenced in sheep, chickens, pigs, and rats. Further research is warranted to determine the dose and method of application of honey bee products in animals.
本综述旨在基于体内研究呈现关于蜜蜂产品对动物影响的当前知识，重点关注其在临床兽医实践中的应用。蜂蜜最经证实的功效是治疗伤口，包括那些感染了耐抗生素微生物的伤口，在马、猫、狗、小鼠和大鼠身上都有证据表明这一点。蜂胶在小鼠、大鼠、狗和猪的多种炎症和疼痛状况中表现出愈合作用，在小鼠和大鼠的肿瘤病例中也有帮助。蜂毒以其在治疗神经病变和关节炎方面的功效最为人所知，在狗、小鼠和大鼠身上都有体现。此外，蜂毒改善了兔子、鸡和猪的繁殖性能、免疫反应和总体健康状况。花粉在刺激鸡的生长和改善肠道微生物群方面有效。蜂王浆因其在提高生育能力方面的功效，可能用于动物繁殖管理，在大鼠、兔子和小鼠身上都有体现。雄蜂幼虫主要因其雄激素作用和对生殖功能的刺激而受到重视，在绵羊、鸡、猪和大鼠身上都有证据表明这一点。有必要进行进一步研究以确定蜜蜂产品在动物中的剂量和应用方法。
