Porojan Liliana, Bejan Flavia Roxana, Tirziu Emil, Gașpar Cristina Mirabela, Moza Alex Cristian, Gherban Mihaela Ionela, Vasiliu Roxana Diana, Matichescu Anamaria
Department of Dental Prostheses Technology (Dental Technology), Center for Advanced Technologies in Dental Prosthodontics, Faculty of Dental Medicine, "Victor Babeș" University of Medicine and Pharmacy Timișoara, Eftimie Murgu Sq. No. 2, 300041 Timișoara, Romania.
Department of Animal Production and Veterinary Public Health, Faculty of Veterinary Medicine Timișoara, University of Life Sciences "King Mihai I" from Romania, Calea Aradului 119, 300645 Timișoara, Romania.
Polymers (Basel). 2024 Aug 20;16(16):2354. doi: 10.3390/polym16162354.
(1) Background: The adhesion and microbiological behaviour of thermoplastic PETG dental appliance surfaces is governed by roughness parameters. The aim of this research was to evaluate the antibiofilm activity of alkaline peroxide-based disinfectant in Candida albicans biofilms on thermoplastic PETG, related to artificial ageing and surface characteristics, on multiscale levels. (2) Methods: In the present study, two PETG materials were investigated: Crystal (Bio Art Dental Equipment, Sao Carlos, Brazil), noted as C, and Duran (Scheu-Dental GmbH, Iserlohn, Germany)-noted as D. Half of the specimens were thermally cycled (TC), resulting in four sample groups, as follows: C, CTC, D, and DTC. Surface roughness was evaluated on different scale topographies. The biofilms were grown on the surfaces. An alkaline peroxide-based disinfectant was used. Statistical analyses were performed. (3) Results: Related to nanoroughness, there are insignificant differences among materials or related to thermocycling. More irregular surfaces are associated with larger grain sizes. After thermocycling, micro-roughness values increase. Disinfectant activity decreases the amount of biofilm developed on the surfaces, significantly in the two groups, but is not correlated to the material and artificial ageing. (4) Conclusion: The impact of surface roughness (Ra) on biofilm constitution is controlled by different scale topographies.
(1) 背景：热塑性聚对苯二甲酸乙二醇酯（PETG）牙科器械表面的附着力和微生物行为受粗糙度参数的影响。本研究的目的是在多尺度水平上评估碱性过氧化物基消毒剂对热塑性PETG上白色念珠菌生物膜的抗生物膜活性，以及与人工老化和表面特性的关系。(2) 方法：在本研究中，研究了两种PETG材料：Crystal（巴西圣卡洛斯的Bio Art牙科设备公司），记为C，以及Duran（德国伊瑟隆的Scheu-Dental GmbH公司），记为D。一半的样本进行了热循环（TC），从而形成了四个样本组，如下：C、CTC、D和DTC。在不同尺度的形貌上评估表面粗糙度。生物膜在这些表面上生长。使用了一种碱性过氧化物基消毒剂。进行了统计分析。(3) 结果：关于纳米粗糙度，材料之间或与热循环相关的纳米粗糙度差异不显著。更不规则的表面与更大的晶粒尺寸相关。热循环后，微观粗糙度值增加。消毒剂活性降低了表面上形成的生物膜数量，在两组中显著降低，但与材料和人工老化无关。(4) 结论：表面粗糙度（Ra）对生物膜构成的影响受不同尺度形貌的控制。
