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饮食预防高血压(DASH)对代谢综合征患者的影响及其潜在机制。

Effect of Dietary Approaches to Stop Hypertension (DASH) on Patients with Metabolic Syndrome and Its Potential Mechanisms.

作者信息

Lv Yangting, Aihemaiti Guliziba, Guo Huirong

机构信息

Department of Neurology, the Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou City, Zhejiang Province, 311500, People's Republic of China.

Department of Medicine, Changji Branch of the First Affiliated Hospital of Xinjiang Medical University, Changji City, Xinjiang Province, 831100, People's Republic of China.

出版信息

Diabetes Metab Syndr Obes. 2024 Aug 23;17:3103-3110. doi: 10.2147/DMSO.S477739. eCollection 2024.

Abstract

Metabolic syndrome (MS) is more prevalent in chronic diseases and, if left untreated, can lead to serious consequences, such as cardiovascular disease (CVD), cerebrovascular disease and type 2 diabetes, which have become significant public health issues globally. Metabolic syndrome is significantly influenced by the daily diet of patients. The dietary approaches to stop hypertension (DASH) diet, originally designed to prevent or control hypertension, offers additional metabolic benefits due to its nutrient composition. The DASH diet recommends the intake of potassium, magnesium, calcium and fibre while limiting total fat, saturated fat and sodium, which is beneficial for patients with MS. Due to its limited fat content and high levels of fibre and calcium, individuals following the DASH diet are less prone to being overweight and obese and have lower concentrations of total and low-density lipoprotein cholesterol. Moreover, the DASH diet can reduce blood pressure and is effective in correcting glucose and insulin abnormalities. This review comprehensively summarises the health benefits of the DASH diet on the risk factors of MS and describes the potential mechanisms based on available evidence.

摘要

代谢综合征(MS)在慢性疾病中更为普遍,若不加以治疗,可能会导致严重后果,如心血管疾病(CVD)、脑血管疾病和2型糖尿病,这些已成为全球重大的公共卫生问题。代谢综合征受患者日常饮食的显著影响。最初旨在预防或控制高血压的饮食方法阻止高血压(DASH)饮食,因其营养成分而具有额外的代谢益处。DASH饮食建议摄入钾、镁、钙和纤维,同时限制总脂肪、饱和脂肪和钠的摄入,这对MS患者有益。由于其脂肪含量有限且纤维和钙含量高,遵循DASH饮食的个体不太容易超重和肥胖,总胆固醇和低密度脂蛋白胆固醇浓度较低。此外,DASH饮食可以降低血压,并有效纠正血糖和胰岛素异常。本综述全面总结了DASH饮食对MS危险因素的健康益处,并根据现有证据描述了潜在机制。

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