凝血因子 VIII 的采购研究：血浆冷冻速率和储存条件对冷沉淀质量的影响。
Studies on the procurement of blood coagulation factor VIII: effects of plasma freezing rate and storage conditions on cryoprecipitate quality.
作者信息
Farrugia A, Prowse C
出版信息
J Clin Pathol. 1985 Apr;38(4):433-7. doi: 10.1136/jcp.38.4.433.
Abstract
Plasma was frozen and stored in different ways before processing to cryoprecipitate by a standard thawing technique. Freezing rate was found to be important with slow freezing having a deleterious effect on cryoprecipitate quality. Storage of frozen plasma at constant temperatures for periods up to six months had no effect on the quality of cryoprecipitate, with no difference being found for plasma stored at -20 degrees C or -40 degrees C. Subjecting frozen plasma to deliberate temperature fluctuations resulted in a considerable increase in the amount of fibrinogen recovered in cryoprecipitate, with the factor VIII yield being relatively unaffected.
摘要
在通过标准解冻技术处理以制备冷沉淀之前，血浆以不同方式冷冻并储存。发现冷冻速率很重要，缓慢冷冻会对冷沉淀质量产生有害影响。在恒定温度下储存冷冻血浆长达六个月对冷沉淀质量没有影响，在-20℃或-40℃储存的血浆之间未发现差异。使冷冻血浆经历有意的温度波动会导致冷沉淀中回收的纤维蛋白原量显著增加，而因子VIII产量相对不受影响。
相似文献
1
Studies on the procurement of blood coagulation factor VIII: effects of plasma freezing rate and storage conditions on cryoprecipitate quality.凝血因子 VIII 的采购研究：血浆冷冻速率和储存条件对冷沉淀质量的影响。
J Clin Pathol. 1985 Apr;38(4):433-7. doi: 10.1136/jcp.38.4.433.
2
Contribution to the optimal use of human blood. VII. Increase of the yield of factor VIII in four-donor cryoprecipitate by an improved processing of blood and plasma.对人类血液合理利用的贡献。VII. 通过改进血液和血浆处理方法提高四供体冷沉淀中凝血因子VIII的产量
Vox Sang. 1976;30(1):1-22. doi: 10.1111/j.1423-0410.1976.tb04830.x.
3
Can storage of thawed cryoprecipitate be extended to more than six hours?解冻后的冷沉淀凝血因子储存时间能否延长至6小时以上？
Am J Clin Pathol. 1990 Aug;94(2):203-6. doi: 10.1093/ajcp/94.2.203.
4
Characterization of factors affecting the stability of frozen heparinized plasma.影响冷冻肝素化血浆稳定性的因素的表征
Vox Sang. 1993;65(4):258-70. doi: 10.1111/j.1423-0410.1993.tb02165.x.
5
Determinants of factor VIII recovery in cryoprecipitate.冷沉淀中凝血因子 VIII 回收率的决定因素
Transfusion. 1975 Jul-Aug;15(4):312-22. doi: 10.1046/j.1537-2995.1975.15476034550.x.
6
Effect of delayed blood processing on the yield of factor VIII in cryoprecipitate and factor VIII concentrate.延迟血液处理对冷沉淀中因子 VIII 及因子 VIII 浓缩物产量的影响。
Transfusion. 1988 Nov-Dec;28(6):566-70. doi: 10.1046/j.1537-2995.1988.28689059033.x.
7
Microwave-thawed plasma for cryoprecipitate production.用于制备冷沉淀的微波解冻血浆。
Vox Sang. 1985;48(2):65-71. doi: 10.1111/j.1423-0410.1985.tb00149.x.
8
Modulation of fibrinogen content in cryoprecipitate by temperature manipulation during plasma processing.血浆处理过程中通过温度控制调节冷沉淀中纤维蛋白原含量
Transfusion. 1992 Oct;32(8):755-9. doi: 10.1046/j.1537-2995.1992.32893032105.x.
9
10
Preparation of cryoprecipitated factor VIII concentrates.冷沉淀凝血因子 VIII 浓缩物的制备。
Transfusion. 1976 Nov-Dec;16(6):616-26. doi: 10.1046/j.1537-2995.1976.16677060245.x.
引用本文的文献
1
Use of Cryoprecipitate in Newborn Infants.冷沉淀在新生儿中的应用。
Newborn (Clarksville). 2023 Jan-Mar;2(1):11-18. doi: 10.5005/jp-journals-11002-0045. Epub 2023 Apr 6.
2
Biochemical and cellular markers differentiate recovered, in-line filtered plasma, and plasma obtained by apheresis methods.生化和细胞标志物可区分恢复的、在线过滤的血浆和通过血浆分离法获得的血浆。
Vox Sang. 2022 Jan;117(1):27-38. doi: 10.1111/vox.13118. Epub 2021 Jun 10.
本文引用的文献
1
Observations on plasma banking and transfusion procedures for haemophilic patients using a quantitative assay for antihaemophilic globulin (AHG).
Br J Haematol. 1959 Jan;5(1):24-30. doi: 10.1111/j.1365-2141.1959.tb04010.x.
2
Relative stability of plasma antihemophilic factor (AHF) under different conditions of storage.血浆抗血友病因子（AHF）在不同储存条件下的相对稳定性。
Am J Med Sci. 1956 Oct;232(4):434-42. doi: 10.1097/00000441-195610000-00010.
3
Current concepts in diagnosis and management of hemophilia.血友病诊断与管理的当前概念。
Hosp Pract (Off Ed). 1982 Oct;17(10):77-84, 89-92. doi: 10.1080/21548331.1982.11702390.
4
Production of cryoprecipitate of intermediate purity in a closed system thaw-siphon process.在封闭系统解冻虹吸过程中生产中等纯度的冷沉淀。
Thromb Haemost. 1981 Aug 28;46(2):543-6.
5
Coagulation abnormalities following intensive plasma exchange on the cell separator. II. Effects on factors I, II, V, VII, VIII, IX, X and antithrombin III.血细胞分离机上进行强化血浆置换后的凝血异常。II. 对因子I、II、V、VII、VIII、IX、X及抗凝血酶III的影响
Br J Haematol. 1981 Aug;48(4):627-34. doi: 10.1111/j.1365-2141.1981.00627.x.
6
Immunologic studies of factor VIII coagulant activity (VIII:C) 1. Assays based on a haemophilic and an acquired antibody to VIII:C.
Thromb Res. 1981;21(4-5):431-45. doi: 10.1016/0049-3848(81)90144-4.
7
Preparation of improved cryoprecipitated factor VIII concentrate. A controlled study of three variables affecting the yield.改良冷沉淀凝血因子 VIII 浓缩物的制备。对影响产量的三个变量的对照研究。
Vox Sang. 1980;38(4):222-8. doi: 10.1111/j.1423-0410.1980.tb02358.x.
8
Heparin and factor VIII.肝素与凝血因子 VIII。
Scand J Haematol Suppl. 1984;40:111-22. doi: 10.1111/j.1600-0609.1984.tb02552.x.
9
Treatment of haemophilia and related disorders in Britain and Northern Ireland during 1976-80: report on behalf of the directors of haemophilia centres in the United Kingdom.1976 - 1980年英国和北爱尔兰血友病及相关疾病的治疗：代表联合王国血友病中心主任的报告
Br Med J (Clin Res Ed). 1983 Mar 19;286(6369):929-33. doi: 10.1136/bmj.286.6369.929.
10
Antihaemophilic globulin: preparation by an improved cryoprecipitation method and clinical use.抗血友病球蛋白：用改良冷沉淀法制备及临床应用
Br Med J. 1967 Apr 8;2(5544):79-85. doi: 10.1136/bmj.2.5544.79.
Zotero 插件