Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
RTI International, USA.
Drug Alcohol Depend. 2024 Oct 1;263:112430. doi: 10.1016/j.drugalcdep.2024.112430. Epub 2024 Aug 28.
Racialized health inequities in substance use-related harms might emerge from differential access to syringe service programs (SSPs). To explore this, we examined the association between county-level racialized environments, other factors, and (1) SSP presence, and (2) per capita syringe and (3) naloxone distribution.
2021 US National Survey of SSP data (n=295/412;72 % response rate) was used to identify SSP presence and the sum of syringes and naloxone doses distributed in 2020 by county. Study measures included racial residential segregation (RRS; i.e., divergence and dissimilarity indexes for Black:Non-Hispanic White & Hispanic:Non-Hispanic White) and covariates (i.e., demographic proportions, urban/suburban/rural classifications, 2020 US presidential Republican vote share, and overdose mortality from 2019). We used logit Generalized Estimating Equations to determine factors associated with county-level SSP presence, and zero inflated negative binomial regression models to determine factors associated with per capita syringe and naloxone distribution.
SSPs were reported in 9 % (283/3106) of US counties. SSP presence was associated with higher divergence and dissimilarity indexes, urban and suburban counties, higher opioid overdose mortality, and lower 2020 Republican presidential vote share. Per capita syringes distributed was associated with lower RRS (divergence and Hispanic:White dissimilarity), lower racially minoritized population proportions and rural counties, while per capita naloxone distribution was associated with lower Hispanic and "other" population proportions, and rural counties.
Racialized environments are associated with SSP presence but not the scope of those programs. Preventing HIV and HCV outbreaks, and overdose deaths requires addressing community level factors that influence SSP implementation and accessibility.
在与物质使用相关的伤害中,种族化的健康不平等可能源于接受注射服务项目(SSP)的机会不同。为了探讨这一点,我们研究了县级种族化环境以及其他因素与(1)SSP 存在情况,(2)人均注射器数量和(3)纳洛酮分布之间的关系。
我们使用了 2021 年美国全国 SSP 数据调查(n=295/412;72%的回复率),以确定 SSP 的存在情况,以及 2020 年每个县分发的注射器和纳洛酮剂量总数。研究指标包括种族居住隔离(RRS;即,黑人和非西班牙裔白人之间以及西班牙裔和非西班牙裔白人之间的离散度和不相似指数)和协变量(即,人口比例、城市/郊区/农村分类、2020 年美国总统共和党选票份额,以及 2019 年的过量死亡率)。我们使用对数广义估计方程确定与县级 SSP 存在情况相关的因素,以及零膨胀负二项回归模型确定与人均注射器和纳洛酮分布相关的因素。
报告了 9%(283/3106)的美国县有 SSP。SSP 的存在与更高的离散度和不相似指数、城市和郊区县、更高的阿片类药物过量死亡率以及 2020 年共和党总统选票份额较低有关。人均注射器的分配与 RRS 较低(离散度和西班牙裔与白人的不相似指数)、种族少数群体比例较低和农村县有关,而人均纳洛酮的分配与西班牙裔和“其他”人口比例较低以及农村县有关。
种族化环境与 SSP 的存在有关,但与这些项目的范围无关。要预防 HIV 和 HCV 爆发以及过量死亡,需要解决影响 SSP 实施和可及性的社区层面因素。