• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

单侧脊髓麻醉用于因主动脉瓣狭窄而具有高心血管风险的老年髋部骨折手术患者是安全有效的。

Unilateral Spinal Anesthesia in Hip Fracture Surgery for Geriatric Patients With High Cardiovascular Risk due to Aortic Stenosis is Safe and Effective.

作者信息

Çağıran Zeynep, Vahabi Arman, Özgül Kazım Koray, Aljasim Omar, Karaman Semra, Özkayın Nadir, Aktuğlu Kemal, Sertöz Nezih

机构信息

Department of Anesthesiology and Reanimation, Ege University School of Medicine, Izmir, Turkey.

Department of Orthopaedics and Traumatology, Ege University School of Medicine, Izmir, Turkey.

出版信息

Geriatr Orthop Surg Rehabil. 2024 Aug 30;15:21514593241280908. doi: 10.1177/21514593241280908. eCollection 2024.

DOI:10.1177/21514593241280908
PMID:39220252
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11366102/
Abstract

INTRODUCTION

Aortic stenosis is a cause of mortality or morbidity. It complicates the selection and management of anesthetic procedures. The aim of this study was to evaluate the efficacy, hemodynamic effects and postoperative outcome of unilateral spinal anesthesia in geriatric patients with hip fractures with moderate or severe aortic stenosis.

MATERIAL AND METHOD

A retrospective observational study was conducted on geriatric high-risk patients with cardiac conditions who underwent surgery for hip fractures under unilateral spinal anesthesia with low-dose hyperbaric bupivacaine. The study period spanned from January 2018 to December 2021. The inclusion criteria were individuals with moderate to severe aortic stenosis, as defined by the American Heart Association Criteria. Data on demographic information, cardiac pathologies, hemodynamic data, data on motor and sensory block, perioperative complications, and mortality rates at 30th and 180th days were collected.

RESULTS

Mortality rates at the 30th day and 180th day were 8.9% (n:4) and 24.4% (n:11), respectively. T6 level was predominantly obtained level of anesthesia (44.4%). Motor and sensory block formation times averaged 7.6 and 4.8 minutes, respectively. Surgical procedures were performed mostly within 1 hour (66.7%), and complications were rare (11.1% hypotension). Initial analgesic effect showed a rapid resolution, with 64.4% of patients requiring analgesic within the first hour postoperatively.

CONCLUSION

In elderly patients with moderate to severe aortic stenosis scheduled for hip fracture surgery, we posit that unilateral spinal anesthesia with ultra-low dose is safe and effective option.

摘要

引言

主动脉瓣狭窄是导致死亡或发病的原因之一。它使麻醉程序的选择和管理变得复杂。本研究的目的是评估单侧脊髓麻醉在患有中度或重度主动脉瓣狭窄的老年髋部骨折患者中的疗效、血流动力学效应和术后结果。

材料与方法

对接受低剂量高压布比卡因单侧脊髓麻醉下髋部骨折手术的老年高危心脏病患者进行了一项回顾性观察研究。研究期间为2018年1月至2021年12月。纳入标准为符合美国心脏协会标准定义的中度至重度主动脉瓣狭窄患者。收集了人口统计学信息、心脏病变、血流动力学数据、运动和感觉阻滞数据、围手术期并发症以及第30天和第180天的死亡率数据。

结果

第30天和第180天的死亡率分别为8.9%(n = 4)和24.4%(n = 11)。主要麻醉平面为T6水平(44.4%)。运动和感觉阻滞形成时间平均分别为7.6分钟和4.8分钟。手术大多在1小时内完成(66.7%),并发症罕见(低血压11.1%)。初始镇痛效果迅速消退,64.4%的患者在术后第一小时内需要镇痛。

结论

对于计划进行髋部骨折手术的中度至重度主动脉瓣狭窄老年患者,我们认为超低剂量单侧脊髓麻醉是一种安全有效的选择。

相似文献

1
Unilateral Spinal Anesthesia in Hip Fracture Surgery for Geriatric Patients With High Cardiovascular Risk due to Aortic Stenosis is Safe and Effective.单侧脊髓麻醉用于因主动脉瓣狭窄而具有高心血管风险的老年髋部骨折手术患者是安全有效的。
Geriatr Orthop Surg Rehabil. 2024 Aug 30;15:21514593241280908. doi: 10.1177/21514593241280908. eCollection 2024.
2
Comparison of two doses of hypobaric bupivacaine in unilateral spinal anesthesia for hip fracture surgery: 5 mg versus 7.5 mg.两种剂量低压布比卡因用于髋部骨折手术单侧脊髓麻醉的比较:5毫克与7.5毫克。
Pan Afr Med J. 2017 Oct 4;28:108. doi: 10.11604/pamj.2017.28.108.11421. eCollection 2017.
3
Single shot spinal anesthesia with very low hyperbaric bupivacaine dose (3.75 mg) for hip fracture repair surgery in the elderly. A randomized, double blinded study.极低剂量重比重布比卡因(3.75毫克)单次注射用于老年髋部骨折修复手术的脊髓麻醉。一项随机双盲研究。
Rev Esp Anestesiol Reanim. 2014 Nov;61(9):481-8. doi: 10.1016/j.redar.2014.02.004. Epub 2014 Jul 21.
4
[Unilateral spinal anesthesia : Literature review and recommendations].[单侧脊髓麻醉:文献综述与建议]
Anaesthesist. 2016 Nov;65(11):847-865. doi: 10.1007/s00101-016-0232-x.
5
The effect of aortic stenosis on elderly hip fracture outcomes: A case control study.主动脉瓣狭窄对老年髋部骨折预后的影响:一项病例对照研究。
Injury. 2016 Feb;47(2):413-8. doi: 10.1016/j.injury.2015.10.015. Epub 2015 Oct 28.
6
Is Anesthesia Technique Associated With a Higher Risk of Mortality or Complications Within 90 Days of Surgery for Geriatric Patients With Hip Fractures?老年髋部骨折患者术后 90 天内,麻醉技术与死亡率或并发症风险增加是否相关?
Clin Orthop Relat Res. 2018 Jun;476(6):1178-1188. doi: 10.1007/s11999.0000000000000147.
7
Comparison between Position Change after Low-Dose Spinal Anesthesia and Higher dose with Sitting Position in Elderly Patients: Block Characteristics, Hemodynamic Changes, and Complications.老年患者低剂量与高剂量脊髓麻醉后坐位体位变化的比较:阻滞特征、血流动力学变化及并发症
Anesth Essays Res. 2019 Jul-Sep;13(3):476-480. doi: 10.4103/aer.AER_101_19.
8
Does Adding Lidocaine to Intrathecal Bupivacaine Affect Hemodynamic Parameters during Hip Fracture Surgery?在髋关节骨折手术中,向鞘内布比卡因中添加利多卡因会影响血流动力学参数吗?
Arch Bone Jt Surg. 2018 Sep;6(5):390-396.
9
Low-dose bupivacaine with sufentanil prevents hypotension after spinal anesthesia for hip repair in elderly patients.低剂量布比卡因联合舒芬太尼可预防老年患者髋关节修复术脊髓麻醉后的低血压。
Acta Anaesthesiol Scand. 2004 Nov;48(10):1240-4. doi: 10.1111/j.1399-6576.2004.00504.x.
10
Effects of bupivacaine or levobupivacaine on cerebral oxygenation during spinal anesthesia in elderly patients undergoing orthopedic surgery for hip fracture: a randomized controlled trial.布比卡因或左旋布比卡因对老年髋部骨折骨科手术患者脊髓麻醉期间脑氧合的影响:一项随机对照试验。
BMC Anesthesiol. 2019 Jan 31;19(1):17. doi: 10.1186/s12871-019-0682-1.

本文引用的文献

1
Aortic Stenosis Management in Patients With Acute Hip Fracture.急性髋部骨折患者的主动脉瓣狭窄管理
JACC Adv. 2024 Apr 3;3(5):100912. doi: 10.1016/j.jacadv.2024.100912. eCollection 2024 May.
2
Hip Fracture Surgery in Severe Aortic Stenosis: A Study of Factors Affecting Mortality.严重主动脉瓣狭窄患者髋关节骨折手术:影响死亡率的因素研究。
Clin Interv Aging. 2022 Aug 4;17:1163-1171. doi: 10.2147/CIA.S360538. eCollection 2022.
3
Severe aortic stenosis is associated with perioperative mortality in proximal femur fracture patients.严重主动脉瓣狭窄与股骨近端骨折患者围手术期死亡率相关。
OTA Int. 2020 May 5;3(2):e054. doi: 10.1097/OI9.0000000000000054. eCollection 2020 Jun.
4
Anaesthesia for hip fracture repair.髋部骨折修复术的麻醉
BJA Educ. 2020 May;20(5):142-149. doi: 10.1016/j.bjae.2020.02.003. Epub 2020 Mar 23.
5
Attributable Mortality of Hip Fracture in Older Patients: A Retrospective Observational Study.老年患者髋部骨折的归因死亡率:一项回顾性观察研究。
J Clin Med. 2020 Jul 24;9(8):2370. doi: 10.3390/jcm9082370.
6
Morbidity and Mortality following Surgery for Hip Fractures in Elderly Patients.老年患者髋部骨折手术后的发病率和死亡率
J Aging Res. 2019 Feb 5;2019:7084657. doi: 10.1155/2019/7084657. eCollection 2019.
7
Association Between Wait Time and 30-Day Mortality in Adults Undergoing Hip Fracture Surgery.髋部骨折手术成年患者等待时间与30天死亡率之间的关联
JAMA. 2017 Nov 28;318(20):1994-2003. doi: 10.1001/jama.2017.17606.
8
Early Surgery Confers 1-Year Mortality Benefit in Hip-Fracture Patients.早期手术可为髋部骨折患者带来 1 年死亡率获益。
J Orthop Trauma. 2018 Mar;32(3):105-110. doi: 10.1097/BOT.0000000000001043.
9
Comparison of Hemodynamic Changes in Unilateral Spinal Anesthesia Versus Epidural Anesthesia Below the T10 Sensory Level in Unilateral Surgeries: a Double-Blind Randomized Clinical Trial.单侧手术中T10感觉平面以下单侧脊髓麻醉与硬膜外麻醉血流动力学变化的比较:一项双盲随机临床试验
Med Arch. 2017 Aug;71(4):274-279. doi: 10.5455/medarh.2017.71.274-279.
10
Central regional anaesthesia in patients with aortic stenosis - a systematic review.主动脉瓣狭窄患者的中枢区域麻醉——一项系统评价
Dan Med J. 2017 Sep;64(9).