Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Center for Hospice Palliative Shared Care, National Cheng Kung University, Tainan, Taiwan.
Support Care Cancer. 2024 Sep 2;32(9):624. doi: 10.1007/s00520-024-08832-5.
The Palliative Care Outcomes Collaboration (PCOC) aims to enhance patient outcomes systematically. However, identifying crucial items and accurately determining PCOC phases remain challenging. This study aims to identify essential PCOC data items and construct a prediction model to accurately classify PCOC phases in terminal patients.
A retrospective cohort study assessed PCOC data items across four PCOC phases: stable, unstable, deteriorating, and terminal. From July 2020 to March 2023, terminal patients were enrolled. A multinomial mixed-effect regression model was used for the analysis of multivariate PCOC repeated measurement data.
The dataset comprised 1933 terminally ill patients from 4 different hospice service settings. A total of 13,219 phases of care were analyzed. There were significant differences in the symptom assessment scale, palliative care problem severity score, Australia-modified Karnofsky performance status, and resource utilization groups-activities of daily living among the four PCOC phases of care. Clinical needs, including pain and other symptoms, declined from unstable to terminal phases, while psychological/spiritual and functional status for bed mobility, eating, and transfers increased. A robust prediction model achieved areas under the curves (AUCs) of 0.94, 0.94, 0.920, and 0.96 for stable, unstable, deteriorating, and terminal phases, respectively.
Critical PCOC items distinguishing between PCOC phases were identified, enabling the development of an accurate prediction model. This model enhances hospice care quality by facilitating timely interventions and adjustments based on patients' PCOC phases.
缓和医疗照护结局合作组织(Palliative Care Outcomes Collaboration,PCOC)旨在有系统地提升病患的预后。然而,确定关键项目并准确判断 PCOC 阶段仍然具有挑战性。本研究旨在识别缓和医疗照护中至关重要的 PCOC 数据项目,并构建一个预测模型,以准确分类末期病患的 PCOC 阶段。
回顾性队列研究评估了四个 PCOC 阶段(稳定、不稳定、恶化和末期)的 PCOC 数据项目。2020 年 7 月至 2023 年 3 月期间,纳入末期病患。采用多项混合效应回归模型对多变量 PCOC 重复测量数据进行分析。
数据集包括来自 4 个不同缓和医疗服务环境的 1933 名末期病患。共分析了 13219 个照护阶段。在四个 PCOC 照护阶段中,症状评估量表、缓和医疗问题严重程度评分、澳大利亚改良 Karnofsky 表现状态和资源利用组-日常生活活动方面存在显著差异。临床需求,包括疼痛和其他症状,从不稳定阶段到末期阶段逐渐减轻,而心理/精神和床旁移动、进食和转移的功能状态则逐渐增加。一个稳健的预测模型在稳定、不稳定、恶化和末期阶段的曲线下面积(AUC)分别达到 0.94、0.94、0.920 和 0.96。
识别 PCOC 阶段之间差异的关键 PCOC 项目已被确定,从而能够开发出一个准确的预测模型。该模型通过根据病患的 PCOC 阶段及时进行干预和调整,提高了缓和医疗照护的质量。