Kudesia G, Robinson E T, Wilson W D, Wilson T S, Stewart I M, Campbell A T, Thomson W, Silver M, Reid D, Urquhart G E
Br Med J (Clin Res Ed). 1985 May 11;290(6479):1406-8. doi: 10.1136/bmj.290.6479.1406.
Of 191 schoolgirls, 128 volunteered to take part in a feasibility study of serotesting before and after rubella vaccination, and all responded to RA 27/3 vaccine. Had the serum samples been taken by a fingerprick method the number of volunteers would probably have increased considerably. A change in policy for rubella vaccination to testing both before and after vaccination would cost no more than the existing policy, would ensure primary response, and would differentiate those women who were protected by the vaccine from those with antibody to wild virus.
在191名女学生中,128人自愿参与风疹疫苗接种前后血清检测的可行性研究,所有人均对RA 27/3疫苗有反应。如果血清样本采用手指采血法采集,志愿者人数可能会大幅增加。将风疹疫苗接种政策改为接种前后都进行检测,成本不会高于现行政策,能确保产生初次反应,还能区分出那些受到疫苗保护的女性和那些具有野生病毒抗体的女性。