Gilmore D, Robinson E T, Gilmour W H, Urquhart G E
Br Med J (Clin Res Ed). 1982 Feb 27;284(6316):628-30. doi: 10.1136/bmj.284.6316.628.
Between November 1979 and January 1980 all patients aged 13-21 years who attended a general practice in Glasgow were tested for their immunity against rubella (single radial haemolysis test). All of the women in the sample should have been vaccinated at 13 as part of the rubella vaccination programme, which began in Glasgow in 1971. The programme excludes boys. Of the 77 females and 64 male patients studied, nine (11.7%) and 10 (15.6%), respectively, were susceptible to the infection. For only 34 women was evidence of vaccination documented in the practice records, and three of those either had failed to seroconvert or had antibody below detectable values. Overall there was no significant differences between the proportion of men and women who were susceptible to the disease. The rubella vaccination programme had clearly failed to reduce the number of susceptible women in this practice. Hence the immune state of all girls should be checked at about 15 years of age, so that as many as possible may be rendered immune before they leave school.
1979年11月至1980年1月期间,对所有在格拉斯哥一家普通诊所就诊的13至21岁患者进行了风疹免疫检测(单向辐射溶血试验)。作为始于1971年的格拉斯哥风疹疫苗接种计划的一部分,样本中的所有女性在13岁时都应接种过疫苗。该计划不包括男孩。在研究的77名女性和64名男性患者中,分别有9名(11.7%)和10名(15.6%)对该感染易感。在诊所记录中,仅有34名女性有接种疫苗的记录,其中3人要么血清转化失败,要么抗体低于可检测值。总体而言,易感男性和女性的比例没有显著差异。风疹疫苗接种计划显然未能减少该诊所中易感女性的数量。因此,应在所有女孩15岁左右时检查其免疫状态,以便尽可能多的女孩在离开学校前获得免疫。