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埃塞俄比亚阿姆哈拉地区德西转诊医院 2 型糖尿病患者的代谢综合征与生活方式因素。

Metabolic syndrome and lifestyle factors among type 2 diabetes mellitus patients in Dessie Referral Hospital, Amhara region, Ethiopia.

机构信息

Department of Nutrition, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.

Department of Nutrition and Dietetics, College of Health Sciences, Mekelle University, Mekelle, Ethiopia.

出版信息

PLoS One. 2020 Nov 2;15(11):e0241432. doi: 10.1371/journal.pone.0241432. eCollection 2020.

Abstract

BACKGROUND

The prevalence of metabolic syndrome is rising at an alarming rate and more common among Type 2 Diabetes Mellitus patients in the world. The risk for cardiovascular disease is greater among individuals who have a combination of Type 2 Diabetes Mellitus and metabolic syndrome compared to those who have either alone.

OBJECTIVE

To assess the proportion of metabolic syndrome and lifestyle factors among Type 2 Diabetes Mellitus Patients in Dessie Referral Hospital, Amhara Region, Ethiopia.

METHODS

A hospital-based cross-sectional study was conducted from February to March 2017 among 343 randomly selected Type 2 Diabetes Mellitus patients. Three definitions of Metabolic syndrome were considered. Multivariable logistic regression analysis was conducted to identify factors associated with metabolic syndrome. Adjusted odds ratio (AOR) with 95% confidence intervals (CI) were reported to show the strength of association. Statistical significance was declared at P-value < 0.05.

RESULT

The proportion of metabolic syndrome was 50.3%, 59.4% and 64.5% according to 2005 International Diabetes Federation, revised ATP III and 2009 harmonized criteria, respectively. Being female (AOR = 2.43; 95% CI = 1.40, 4.21), consumption of red meat (AOR = 2.61; 95% CI = 1.28, 5.33), sedentary leisure time activity (AOR = 2.65; 95% CI = 1.47, 4.78), coffee intake (AOR = 0.43; 95% CI = 0.21, 0.86), BMI ≥ 25 kg/m2 (AOR = 9.59; 95% CI = 4.98, 18.47), 40-49 years of age (AOR = 2.74, 95% CI = (1.02, 7.37), 50-59 years of age (AOR = 4.22; 95% CI = 1.60, 11.11) and ≥70 years of age (AOR = 4.51, 95% CI = 1.44, 14.15) were significantly associated with metabolic syndrome.

CONCLUSION AND RECOMMENDATION

The proportion of metabolic syndrome was high among Type 2 Diabetes Mellitus patients. Overweight and obesity, being female, age of respondent, intake of coffee, regular red meat consumption, and sedentary leisure-time activity were factors associated with metabolic syndrome. Counseling of Type 2 Diabetes Mellitus patients on the need for spending leisure time with activities, intake of coffee, control of body weight, and avoidance of regular red meat consumption is recommended.

摘要

背景

代谢综合征的患病率呈惊人的速度上升,在世界范围内 2 型糖尿病患者中更为常见。与仅有 2 型糖尿病的个体相比,同时患有 2 型糖尿病和代谢综合征的个体发生心血管疾病的风险更高。

目的

评估埃塞俄比亚阿姆哈拉地区德西转诊医院 2 型糖尿病患者代谢综合征及生活方式因素的比例。

方法

2017 年 2 月至 3 月期间,对 343 名随机选择的 2 型糖尿病患者进行了基于医院的横断面研究。考虑了三种代谢综合征的定义。采用多变量逻辑回归分析确定与代谢综合征相关的因素。报告了调整后的优势比(AOR)和 95%置信区间(CI)以显示关联的强度。P 值 < 0.05 表示具有统计学意义。

结果

根据 2005 年国际糖尿病联盟、修订后的 ATP III 和 2009 年协调标准,代谢综合征的比例分别为 50.3%、59.4%和 64.5%。女性(AOR=2.43;95%CI=1.40,4.21)、食用红肉(AOR=2.61;95%CI=1.28,5.33)、久坐的休闲时间活动(AOR=2.65;95%CI=1.47,4.78)、摄入咖啡(AOR=0.43;95%CI=0.21,0.86)、BMI≥25kg/m2(AOR=9.59;95%CI=4.98,18.47)、40-49 岁(AOR=2.74,95%CI=(1.02,7.37)、50-59 岁(AOR=4.22;95%CI=1.60,11.11)和≥70 岁(AOR=4.51,95%CI=1.44,14.15)与代谢综合征显著相关。

结论和建议

2 型糖尿病患者代谢综合征的比例较高。超重和肥胖、女性、受访者年龄、咖啡摄入量、定期食用红肉和久坐的休闲时间活动是与代谢综合征相关的因素。建议对 2 型糖尿病患者进行咨询,使其了解需要通过活动来度过闲暇时间、控制体重和避免定期食用红肉的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d6c/7605694/b2460aeff4d9/pone.0241432.g001.jpg

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