Farghadani Maryam, Sanei Parinaz
Department of Radiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Adv Biomed Res. 2024 Apr 27;13:36. doi: 10.4103/abr.abr_221_21. eCollection 2024.
Breast cancer is considered one of the most prevalent cancers among females worldwide. The aim of this study was to assess the magnetic resonance imaging (MRI) patterns of female breast cancer, and also the prevalence of mass-like and nonmass-like lesions among these patients.
32 patients with proven breast cancer (based on their pathologic findings and background parenchymal enhancement [BPE] of their magnetic resonance [MR] images) were included in this cross-sectional study which was performed from 2017 to 2019 in Isfahan, Iran, using a1.5 Tesla (Achieva Philips, Netherland) MRI scanner system. The MR sequences (noncontrast image and at least two contrast-enhanced images) were done in the prone position for studied patients.
It was found that 68.8% ( = 44) and 31.2% ( = 20) of breast cancers were suffered from moderate and severe BPE, respectively. Furthermore, the prevalence of mass-like nonmass-like and both tumors were 43.8%, 43.8%, and 12.4%, respectively. Pathological studies indicated that 50%, 37.5%, and 12.5% of cancers were ductal carcinoma (DCIS), invasive ductal carcinoma (IDC), and DCIS, respectively. In addition, a significant relationship between MRI characteristics and pathologic findings was found for IDC and DCIS ( = 0.03).
Based on the results of this study, the relationship between BPE level and MRI finding including mass-like or nonmass-like lesions in biopsy-proven breast cancers was not significant.
乳腺癌被认为是全球女性中最常见的癌症之一。本研究的目的是评估女性乳腺癌的磁共振成像(MRI)模式,以及这些患者中肿块样和非肿块样病变的患病率。
本横断面研究纳入了32例经病理证实患有乳腺癌的患者(基于其病理结果和磁共振(MR)图像的背景实质强化[BPE]),该研究于2017年至2019年在伊朗伊斯法罕使用1.5特斯拉(荷兰飞利浦Achieva)MRI扫描仪系统进行。对研究患者在俯卧位进行MR序列检查(平扫图像和至少两幅增强图像)。
发现分别有68.8%(=44)和31.2%(=20)的乳腺癌患者存在中度和重度BPE。此外,肿块样、非肿块样及两者皆有的肿瘤患病率分别为43.8%、43.8%和12.4%。病理研究表明,分别有50%、37.5%和12.5%的癌症为导管原位癌(DCIS)、浸润性导管癌(IDC)和DCIS。此外,发现IDC和DCIS的MRI特征与病理结果之间存在显著相关性(=0.03)。
基于本研究结果,在经活检证实的乳腺癌中,BPE水平与包括肿块样或非肿块样病变在内的MRI表现之间的关系不显著。