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中国四、五线城市围绝经期激素治疗的知识和认知。

Knowledge and Awareness Toward Menopausal Hormone Therapy in a Fourth-Tier City of China.

机构信息

Department of Gynecology, Qinhuangdao Maternity and Child Health Hospital, Qinhuangdao, Hebei, China.

Department of Clinical Medicine, Qinhuangdao Maternity and Child Health Hospital, Qinhuangdao, Hebei, China.

出版信息

Med Sci Monit. 2024 Sep 6;30:e942577. doi: 10.12659/MSM.942577.

DOI:10.12659/MSM.942577
PMID:39238178
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11382616/
Abstract

BACKGROUND Menopausal hormone therapy (MHT) has been receiving increasing attention in developed countries. The purpose of this study was to investigate understanding of menopause and acceptance of MHT in Qinhuangdao, China. MATERIAL AND METHODS We analyzed data from 186 perimenopausal patients on topics including menopausal symptoms and acceptance of and adherence to MHT treatment. We also surveyed 100 medical staff on menopausal-related knowledge. RESULTS Group A consisted of 41 patients treated with MHT for more than 1 cycle, group B consisted of 49 patients who had received MHT but had stopped it for more than 3 months, and group C consisted of 96 patients who never received MHT. There was a significant difference among them in modified Kupermann scores before treatment (P<0.05), but the difference disappeared after MHT (P>0.05). In group C, 32 patients (33%) were unaware of MHT, 60 (62.5%) were worried about the risk of breast/endometrial cancer, 24 (25%) were worried about high costs, and 67 (70%) had no obvious symptoms and did not want MHT. Similarly, in group B, most people stopped MHT for fear of breast or endometrial cancer. A survey targeting 100 medical staff in our hospital found 14 people (14%) knew about and were willing to accept MHT, 44 people (44%) knew about MHT but were afraid to use it, and 42 people (42%) did not know about MHT at all. CONCLUSIONS MHT has not yet been accepted by the majority of people, even medical staff, in Qinhuangdao, China, and much further progress is needed.

摘要

背景

绝经激素治疗(MHT)在发达国家受到越来越多的关注。本研究旨在调查中国秦皇岛地区对绝经和接受 MHT 的认识。

材料与方法

我们分析了 186 例围绝经期患者的资料,包括绝经症状以及对 MHT 治疗的接受和依从性。我们还对 100 名医务人员进行了与绝经相关的知识调查。

结果

A 组为 41 例接受 MHT 治疗超过 1 个周期的患者,B 组为 49 例接受 MHT 但停药超过 3 个月的患者,C 组为 96 例从未接受 MHT 的患者。治疗前改良 Kupermann 评分有显著差异(P<0.05),但 MHT 后差异消失(P>0.05)。在 C 组中,32 例(33%)不知道 MHT,60 例(62.5%)担心乳腺癌/子宫内膜癌风险,24 例(25%)担心费用高,67 例(70%)没有明显症状且不想接受 MHT。同样,在 B 组中,大多数人停止 MHT 是因为担心乳腺癌或子宫内膜癌。针对我院 100 名医务人员的调查发现,14 人(14%)了解并愿意接受 MHT,44 人(44%)了解 MHT 但不敢使用,42 人(42%)根本不了解 MHT。

结论

MHT 尚未被秦皇岛的大多数人接受,甚至包括医务人员,还需要进一步的推广。

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Postmenopausal Osteoporosis: Menopause Hormone Therapy and Selective Estrogen Receptor Modulators.绝经后骨质疏松症:绝经激素治疗与选择性雌激素受体调节剂
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