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化学风险评估中使用的术语与系统评价中使用的术语的交叉映射:研究方案。

Cross-mapping of terms used in chemical risk assessment with those used in systematic review: research protocol.

作者信息

Svendsen Camilla, Mathisen Gro H, Vist Gunn E, Husøy Trine, Ames Heather M, Beronius Anna, Di Consiglio Emma, Druwe Ingrid, Hartung Thomas, Hoffmann Sebastian, Hooijmans Carlijn R, Machera Kyriaki, Robinson Joshua F, Roggen Erwin, Rooney Andrew A, Roth Nicolas, Spilioti Eliana, Spyropoulou Anastasia, Tcheremenskaia Olga, Testai Emanuela, Vinken Mathieu, Whaley Paul

机构信息

Norwegian Scientific Committee for Food and Environment, Norwegian Institute of Public Health, Oslo, Norway.

Department of Chemical Toxicology, Norwegian Institute of Public Health, Oslo, Norway.

出版信息

Evid Based Toxicol. 2024;2(1). doi: 10.1080/2833373x.2024.2371285. Epub 2024 Jul 12.

DOI:10.1080/2833373x.2024.2371285
PMID:39239089
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11376327/
Abstract

The focus on implementation of systematic review (SR) principles in chemical risk assessments (CRAs) is growing as it has the potential to advance the rigour and transparency of the CRAs. However, the SR and CRA communities use their own specific terminologies. Understanding the meaning of core SR and CRA terms and where they overlap is critical for application of SR methods and principles in CRAs. Moreover, it will increase the possibility for cross-sectorial collaboration, avoid misunderstandings, and improve communication among risk assessors, researchers, and policy makers. We present a process for the cross-mapping of core CRA terms and core SR terms. Core terms for study appraisal, evidence synthesis and integration used in the SR and CRA communities will be included. The outcome will be an overview of how core SR terms map onto core CRA terms and vice versa, and a description of the relationship and conceptual overlap between the terms. The cross-mapping is divided in three phases, where in the first phase the core SR and CRA terms will be identified. In the second phase, existing SR and CRA definitions will be mapped. In the third phase, descriptions of the relationship and conceptual overlap between the terms will be derived. The third phase will include weekly one-hour online meetings for SR and CRA experts.

摘要

随着系统评价(SR)原则在化学风险评估(CRA)中的实施受到越来越多的关注,因为它有可能提高CRA的严谨性和透明度。然而,SR和CRA领域使用各自特定的术语。理解SR和CRA核心术语的含义以及它们的重叠之处,对于在CRA中应用SR方法和原则至关重要。此外,这将增加跨部门合作的可能性,避免误解,并改善风险评估人员、研究人员和政策制定者之间的沟通。我们提出了一个核心CRA术语和核心SR术语交叉映射的过程。将纳入SR和CRA领域用于研究评估、证据综合与整合的核心术语。结果将是一份关于核心SR术语如何映射到核心CRA术语以及反之亦然的概述,以及对这些术语之间关系和概念重叠的描述。交叉映射分为三个阶段,在第一阶段将确定核心SR和CRA术语。在第二阶段,将对现有的SR和CRA定义进行映射。在第三阶段,将得出这些术语之间关系和概念重叠的描述。第三阶段将包括为SR和CRA专家举办的每周一小时在线会议。