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比较泵流量类型(脉动或非脉动)对冠状动脉手术后术后神经认知功能的影响。

Comparison of the Effect of Pump Flow Type (Pulsatile or Non-Pulsatile) on Postoperative Neurocognitive Functions in Coronary Artery Surgery.

机构信息

Department of Cardiovascular Surgery, Faculty of Medicine, Ordu University, Ordu, Turkey.

Department of Cardiovascular Surgery, Faculty of Medicine, Atatürk University, Erzurum, Turkey.

出版信息

Braz J Cardiovasc Surg. 2024 Sep 6;39(5):e20230345. doi: 10.21470/1678-9741-2023-0345.

DOI:10.21470/1678-9741-2023-0345
PMID:39241185
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11379152/
Abstract

INTRODUCTION

The effect of pump flow type on perfusion in coronary surgery using cardiopulmonary bypass (CPB) is discussed. We aimed to evaluate the effect of pump flow type on cognitive functions with neurocognitive function tests.

METHODS

One hundred patients who underwent isolated coronary artery bypass surgery between November 2020 and July 2021 were divided into two equa groups. Groups were formed according to pump flow type pulsatile (Group 1) and non-pulsatile (Group 2). Clock drawing test (CDT) and standardized mini mental test (SMMT) were performed on the patients in both groups in the preoperative period, on the 1st preoperative day, and on the day before discharge. Neurocognitive effects were compared with all follow-up parameters.

RESULTS

There was no difference between the groups in terms of demographic data and in terms of neurocognitive tests performed before the operation. SMMT on postoperative day 1 (Group I: 27.64 ± 1.05; Group II: 24.44 ± 1.64; P=0.001) and CDT (Group I: 5.4 ± 0.54; Group II: 4 .66 ± 0.52; P=0.001), and SMMT on the day before discharge (Group I: 27.92 ± 1.16; Group II: 24.66 ± 1.22; P=0.001) and CDT (Group I: 5 It was calculated as .66 ± 0.48; Group II: 5.44 ± 0.5; P=0.001). The duration of intensive care and hospitalization were higher in the non-pulsatile group.

CONCLUSION

We think that the type of pump flow used in coronary artery bypass surgery using CPB is effective in terms of neurocognitive functions and that pulsatile flow makes positive contributions to this issue.

摘要

介绍

讨论了体外循环(CPB)下冠状动脉手术中泵流量类型对灌注的影响。我们旨在通过神经认知功能测试评估泵流量类型对认知功能的影响。

方法

将 2020 年 11 月至 2021 年 7 月期间接受单纯冠状动脉旁路手术的 100 例患者分为两组。根据泵流量类型(搏动组 1 组和非搏动组 2 组)将患者分为两组。两组患者均在术前、术前第 1 天和出院前进行画钟测验(CDT)和标准化简易精神状态检查(SMMT)。比较所有随访参数的神经认知效应。

结果

两组患者在人口统计学数据和手术前进行的神经认知测试方面无差异。术后第 1 天的 SMMT(组 1:27.64±1.05;组 2:24.44±1.64;P=0.001)和 CDT(组 1:5.4±0.54;组 2:4.66±0.52;P=0.001),以及出院前一天的 SMMT(组 1:27.92±1.16;组 2:24.66±1.22;P=0.001)和 CDT(组 1:5.66±0.48;组 2:5.44±0.5;P=0.001)差异有统计学意义。非搏动组的重症监护和住院时间较长。

结论

我们认为 CPB 下冠状动脉旁路手术中使用的泵流量类型对神经认知功能有效,搏动流量对此问题有积极贡献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85e1/11379152/326d5ff88319/bjcvs-39-05-e20230345-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85e1/11379152/bd004bc9f5a6/bjcvs-39-05-e20230345-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85e1/11379152/326d5ff88319/bjcvs-39-05-e20230345-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85e1/11379152/bd004bc9f5a6/bjcvs-39-05-e20230345-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85e1/11379152/326d5ff88319/bjcvs-39-05-e20230345-g02.jpg

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