Sergeeva N S, Vasil'ev M Iu
Eksp Onkol. 1985;7(2):64-7.
Immunodiffusion technique was used to study the lactoferrin (LF) distribution in human fetal, normal and tumour tissue extracts. If was found that LF concentration in lung tumour extracts was higher than in normal lung one. Indirect immunoperoxidase method revealed LF in alveolar macrophages of normal and tumour lung tissues, in afflux of these cells around the tumour cells, but never--in the original lung cancer cells. It is suggested that LF is not a lung tumour-associated antigen.
采用免疫扩散技术研究乳铁蛋白（LF）在人胎儿、正常及肿瘤组织提取物中的分布。结果发现，肺肿瘤提取物中的LF浓度高于正常肺组织。间接免疫过氧化物酶法显示，LF存在于正常和肿瘤肺组织的肺泡巨噬细胞中，以及这些细胞在肿瘤细胞周围的聚集处，但在原发性肺癌细胞中从未发现。提示LF不是一种与肺肿瘤相关的抗原。
